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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2C2
All Species:
15.15
Human Site:
S342
Identified Species:
27.78
UniProt:
P49116
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49116
NP_003289.2
596
65414
S342
I
D
T
S
G
G
G
S
I
H
V
I
S
R
D
Chimpanzee
Pan troglodytes
XP_001158452
596
65396
S342
I
D
T
S
G
G
G
S
I
H
V
I
S
R
D
Rhesus Macaque
Macaca mulatta
XP_001091445
632
69119
N377
A
N
L
S
E
S
L
N
N
G
D
T
S
E
I
Dog
Lupus familis
XP_541755
633
69174
G379
I
D
A
S
G
G
G
G
I
H
V
I
S
R
D
Cat
Felis silvestris
Mouse
Mus musculus
P49117
596
65221
S342
I
D
A
S
G
G
G
S
I
H
V
I
S
R
D
Rat
Rattus norvegicus
P55094
596
65326
S342
I
D
A
S
G
G
G
S
I
H
V
I
S
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506287
596
65629
N342
M
D
P
A
G
G
G
N
I
H
V
I
S
R
D
Chicken
Gallus gallus
O42101
501
57084
T255
S
Y
M
D
G
Y
Q
T
S
S
P
A
S
I
P
Frog
Xenopus laevis
Q6GN21
637
70767
C383
S
T
Q
G
S
S
E
C
L
G
S
N
A
N
L
Zebra Danio
Brachydanio rerio
Q06725
411
45463
N165
P
G
Q
Y
A
L
T
N
G
D
P
L
N
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
M297
Q
I
A
N
G
D
P
M
G
I
A
G
F
N
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4B8
615
68010
T367
T
T
R
L
L
F
L
T
V
H
F
V
K
D
S
Sea Urchin
Strong. purpuratus
Q26622
583
63834
D322
E
A
G
D
L
S
I
D
Q
S
A
N
G
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
86.2
93.2
N.A.
98.3
97.8
N.A.
94.1
24.3
57.9
29.8
N.A.
20.8
N.A.
21.1
51.3
Protein Similarity:
100
100
86.5
93.3
N.A.
98.8
98.8
N.A.
97.6
41.2
72.5
43.9
N.A.
37
N.A.
42.9
65.6
P-Site Identity:
100
100
13.3
86.6
N.A.
93.3
93.3
N.A.
73.3
13.3
0
0
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
100
26.6
86.6
N.A.
93.3
93.3
N.A.
93.3
20
13.3
20
N.A.
13.3
N.A.
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
31
8
8
0
0
0
0
0
16
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
47
0
16
0
8
0
8
0
8
8
0
0
8
47
% D
% Glu:
8
0
0
0
8
0
8
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
8
0
8
0
0
% F
% Gly:
0
8
8
8
62
47
47
8
16
16
0
8
8
16
8
% G
% His:
0
0
0
0
0
0
0
0
0
54
0
0
0
0
8
% H
% Ile:
39
8
0
0
0
0
8
0
47
8
0
47
0
8
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
8
8
16
8
16
0
8
0
0
8
0
0
8
% L
% Met:
8
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
0
24
8
0
0
16
8
16
0
% N
% Pro:
8
0
8
0
0
0
8
0
0
0
16
0
0
0
8
% P
% Gln:
8
0
16
0
0
0
8
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
47
0
% R
% Ser:
16
0
0
47
8
24
0
31
8
16
8
0
62
0
16
% S
% Thr:
8
16
16
0
0
0
8
16
0
0
0
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
47
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _