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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2C2
All Species:
27.88
Human Site:
Y380
Identified Species:
51.11
UniProt:
P49116
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49116
NP_003289.2
596
65414
Y380
M
P
S
P
M
P
E
Y
L
N
V
H
Y
I
C
Chimpanzee
Pan troglodytes
XP_001158452
596
65396
Y380
M
P
S
P
M
P
E
Y
L
N
V
H
Y
I
C
Rhesus Macaque
Macaca mulatta
XP_001091445
632
69119
S415
T
D
S
S
S
S
P
S
L
A
D
G
I
D
T
Dog
Lupus familis
XP_541755
633
69174
Y417
M
P
S
P
M
P
E
Y
L
N
V
H
Y
I
C
Cat
Felis silvestris
Mouse
Mus musculus
P49117
596
65221
Y380
M
P
S
P
M
P
E
Y
L
N
V
H
Y
I
C
Rat
Rattus norvegicus
P55094
596
65326
Y380
M
P
S
P
M
P
E
Y
L
N
V
H
Y
I
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506287
596
65629
Y380
M
P
S
P
M
P
E
Y
L
N
V
H
Y
I
C
Chicken
Gallus gallus
O42101
501
57084
R293
L
Q
Q
E
Q
A
N
R
S
K
H
E
K
L
N
Frog
Xenopus laevis
Q6GN21
637
70767
Y421
M
P
S
P
M
P
E
Y
L
N
V
H
Y
I
C
Zebra Danio
Brachydanio rerio
Q06725
411
45463
I203
Q
C
M
Q
P
N
N
I
M
G
I
E
N
I
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
I335
Q
C
M
Q
P
N
N
I
M
G
I
D
N
I
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4B8
615
68010
K405
A
L
M
Q
T
A
D
K
I
K
L
G
Q
L
L
Sea Urchin
Strong. purpuratus
Q26622
583
63834
F360
T
P
S
P
M
P
Q
F
L
N
V
H
Y
I
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
86.2
93.2
N.A.
98.3
97.8
N.A.
94.1
24.3
57.9
29.8
N.A.
20.8
N.A.
21.1
51.3
Protein Similarity:
100
100
86.5
93.3
N.A.
98.8
98.8
N.A.
97.6
41.2
72.5
43.9
N.A.
37
N.A.
42.9
65.6
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
100
0
100
13.3
N.A.
13.3
N.A.
0
80
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
100
13.3
100
26.6
N.A.
26.6
N.A.
26.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
16
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
77
% C
% Asp:
0
8
0
0
0
0
8
0
0
0
8
8
0
8
0
% D
% Glu:
0
0
0
8
0
0
54
0
0
0
0
16
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
16
0
16
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
62
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
16
8
0
16
0
8
77
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
16
0
0
8
0
0
% K
% Leu:
8
8
0
0
0
0
0
0
70
0
8
0
0
16
8
% L
% Met:
54
0
24
0
62
0
0
0
16
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
16
24
0
0
62
0
0
16
0
8
% N
% Pro:
0
62
0
62
16
62
8
0
0
0
0
0
0
0
0
% P
% Gln:
16
8
8
24
8
0
8
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
70
8
8
8
0
8
8
0
0
0
0
0
0
% S
% Thr:
16
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
62
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
62
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _