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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTH2R
All Species:
9.39
Human Site:
S483
Identified Species:
29.52
UniProt:
P49190
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49190
NP_005039.1
550
62236
S483
G
K
A
A
K
I
A
S
R
Q
P
D
S
H
I
Chimpanzee
Pan troglodytes
XP_526012
550
62337
S483
G
K
A
A
K
I
S
S
R
Q
P
D
S
H
I
Rhesus Macaque
Macaca mulatta
XP_001108598
550
62214
S483
G
K
A
A
K
I
A
S
R
Q
P
D
S
H
I
Dog
Lupus familis
XP_545621
458
51038
R392
A
E
V
S
K
L
Q
R
T
A
V
K
L
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91V95
546
61890
C480
G
K
P
T
K
N
A
C
R
Q
I
D
S
H
V
Rat
Rattus norvegicus
P70555
546
61751
C480
S
K
P
A
K
T
A
C
R
Q
I
D
S
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90812
420
48581
S354
I
V
F
I
Y
F
N
S
F
L
E
S
F
Q
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693292
593
67360
R468
R
I
Y
R
C
T
S
R
P
S
V
G
S
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.8
22.7
N.A.
82.9
81
N.A.
N.A.
27.6
N.A.
56.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
98.7
38
N.A.
89
87.6
N.A.
N.A.
43.2
N.A.
69.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
6.6
N.A.
60
60
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
66.6
66.6
N.A.
N.A.
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
38
50
0
0
50
0
0
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
13
0
0
25
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
63
0
0
0
% D
% Glu:
0
13
0
0
0
0
0
0
0
0
13
0
0
0
0
% E
% Phe:
0
0
13
0
0
13
0
0
13
0
0
0
13
0
0
% F
% Gly:
50
0
0
0
0
0
0
0
0
0
0
13
0
13
25
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
63
0
% H
% Ile:
13
13
0
13
0
38
0
0
0
0
25
0
0
0
38
% I
% Lys:
0
63
0
0
75
0
0
0
0
0
0
13
0
0
0
% K
% Leu:
0
0
0
0
0
13
0
0
0
13
0
0
13
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
13
13
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
25
0
0
0
0
0
13
0
38
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
13
0
0
63
0
0
0
13
0
% Q
% Arg:
13
0
0
13
0
0
0
25
63
0
0
0
0
0
0
% R
% Ser:
13
0
0
13
0
0
25
50
0
13
0
13
75
0
0
% S
% Thr:
0
0
0
13
0
25
0
0
13
0
0
0
0
0
13
% T
% Val:
0
13
13
0
0
0
0
0
0
0
25
0
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
13
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _