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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGM4
All Species:
10.3
Human Site:
S459
Identified Species:
25.19
UniProt:
P49221
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49221
NP_003232.2
684
77145
S459
D
H
A
F
L
L
L
S
S
E
R
E
H
R
R
Chimpanzee
Pan troglodytes
NP_001124381
684
77202
S459
D
H
A
F
L
L
L
S
S
E
R
E
H
R
R
Rhesus Macaque
Macaca mulatta
XP_001113577
818
89983
S566
E
T
A
A
A
H
G
S
K
P
N
V
Y
A
N
Dog
Lupus familis
XP_542931
747
84220
F503
R
K
A
V
R
K
L
F
G
V
E
A
P
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZH1
670
75572
S446
A
K
A
S
G
K
P
S
D
D
K
L
N
S
R
Rat
Rattus norvegicus
Q99041
667
75568
A438
G
S
P
E
E
R
K
A
M
E
K
A
S
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513197
792
88725
S564
E
K
A
C
S
Y
L
S
C
E
D
G
P
E
A
Chicken
Gallus gallus
Q01841
689
77951
S464
S
K
A
E
H
E
K
S
S
L
G
E
Q
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919916
757
84446
D509
M
Y
K
Q
Y
P
P
D
S
L
E
G
T
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001154909
740
83070
A515
Y
N
A
S
R
Y
V
A
K
N
K
N
F
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
32.1
34.9
N.A.
53.3
54.5
N.A.
43.1
34.2
N.A.
33
N.A.
N.A.
N.A.
N.A.
31.8
Protein Similarity:
100
99.2
49.3
52.3
N.A.
70.7
72.2
N.A.
60.3
52.8
N.A.
52.9
N.A.
N.A.
N.A.
N.A.
51.6
P-Site Identity:
100
100
13.3
20
N.A.
20
6.6
N.A.
26.6
26.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
26.6
20
N.A.
40
26.6
N.A.
33.3
26.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
80
10
10
0
0
20
0
0
0
20
0
10
20
% A
% Cys:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
20
0
0
0
0
0
0
10
10
10
10
0
0
0
0
% D
% Glu:
20
0
0
20
10
10
0
0
0
40
20
30
0
20
10
% E
% Phe:
0
0
0
20
0
0
0
10
0
0
0
0
10
0
0
% F
% Gly:
10
0
0
0
10
0
10
0
10
0
10
20
0
20
0
% G
% His:
0
20
0
0
10
10
0
0
0
0
0
0
20
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
40
10
0
0
20
20
0
20
0
30
0
0
0
20
% K
% Leu:
0
0
0
0
20
20
40
0
0
20
0
10
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
10
10
10
10
0
10
% N
% Pro:
0
0
10
0
0
10
20
0
0
10
0
0
20
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
10
10
0
% Q
% Arg:
10
0
0
0
20
10
0
0
0
0
20
0
0
30
40
% R
% Ser:
10
10
0
20
10
0
0
60
40
0
0
0
10
10
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
10
0
0
10
0
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
0
10
20
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _