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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGM4
All Species:
8.79
Human Site:
S545
Identified Species:
21.48
UniProt:
P49221
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49221
NP_003232.2
684
77145
S545
E
V
T
L
T
L
D
S
K
T
Y
I
N
S
L
Chimpanzee
Pan troglodytes
NP_001124381
684
77202
S545
E
V
T
L
T
L
D
S
K
T
Y
I
N
S
L
Rhesus Macaque
Macaca mulatta
XP_001113577
818
89983
A652
D
R
V
T
M
P
V
A
Y
K
E
Y
R
P
H
Dog
Lupus familis
XP_542931
747
84220
S609
K
K
I
P
I
T
I
S
Y
S
Q
Y
K
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZH1
670
75572
A531
R
V
F
L
T
M
D
A
S
Y
Y
I
Y
K
L
Rat
Rattus norvegicus
Q99041
667
75568
S528
E
V
S
L
S
M
D
S
S
F
Y
I
Y
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513197
792
88725
E652
I
E
V
P
V
H
L
E
A
S
S
Y
V
G
S
Chicken
Gallus gallus
Q01841
689
77951
E549
V
P
L
R
I
L
Y
E
Q
Y
G
P
N
L
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919916
757
84446
L619
E
T
V
E
W
T
L
L
Y
D
H
Y
K
D
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001154909
740
83070
E601
E
T
E
T
F
T
V
E
A
A
D
Y
I
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
32.1
34.9
N.A.
53.3
54.5
N.A.
43.1
34.2
N.A.
33
N.A.
N.A.
N.A.
N.A.
31.8
Protein Similarity:
100
99.2
49.3
52.3
N.A.
70.7
72.2
N.A.
60.3
52.8
N.A.
52.9
N.A.
N.A.
N.A.
N.A.
51.6
P-Site Identity:
100
100
0
6.6
N.A.
46.6
53.3
N.A.
0
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
13.3
20
N.A.
60
73.3
N.A.
6.6
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
20
20
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
40
0
0
10
10
0
0
10
10
% D
% Glu:
50
10
10
10
0
0
0
30
0
0
10
0
0
10
10
% E
% Phe:
0
0
10
0
10
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
20
% H
% Ile:
10
0
10
0
20
0
10
0
0
0
0
40
10
0
0
% I
% Lys:
10
10
0
0
0
0
0
0
20
10
0
0
20
20
0
% K
% Leu:
0
0
10
40
0
30
20
10
0
0
0
0
0
10
40
% L
% Met:
0
0
0
0
10
20
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
30
0
0
% N
% Pro:
0
10
0
20
0
10
0
0
0
0
0
10
0
20
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% Q
% Arg:
10
10
0
10
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
10
0
10
0
0
40
20
20
10
0
0
20
10
% S
% Thr:
0
20
20
20
30
30
0
0
0
20
0
0
0
0
10
% T
% Val:
10
40
30
0
10
0
20
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
30
20
40
50
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _