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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGM4
All Species:
19.39
Human Site:
Y440
Identified Species:
47.41
UniProt:
P49221
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49221
NP_003232.2
684
77145
Y440
D
I
T
Y
E
Y
K
Y
P
E
G
S
S
E
E
Chimpanzee
Pan troglodytes
NP_001124381
684
77202
Y440
D
I
T
Y
E
Y
K
Y
P
E
G
S
S
E
E
Rhesus Macaque
Macaca mulatta
XP_001113577
818
89983
H547
D
I
T
Y
L
Y
K
H
P
E
G
S
D
A
E
Dog
Lupus familis
XP_542931
747
84220
Y484
D
I
T
G
L
Y
K
Y
P
E
G
S
R
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZH1
670
75572
F427
D
I
T
L
Q
Y
R
F
P
E
G
S
P
E
E
Rat
Rattus norvegicus
Q99041
667
75568
R419
K
M
V
G
E
N
R
R
Q
D
I
T
L
H
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513197
792
88725
F545
D
I
T
A
Q
Y
K
F
T
E
G
S
P
E
E
Chicken
Gallus gallus
Q01841
689
77951
Y445
D
I
T
H
T
Y
K
Y
P
E
G
S
E
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919916
757
84446
Y490
D
V
T
H
L
Y
K
Y
P
E
G
N
N
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001154909
740
83070
Y496
D
I
T
E
E
Y
K
Y
K
E
G
S
S
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
32.1
34.9
N.A.
53.3
54.5
N.A.
43.1
34.2
N.A.
33
N.A.
N.A.
N.A.
N.A.
31.8
Protein Similarity:
100
99.2
49.3
52.3
N.A.
70.7
72.2
N.A.
60.3
52.8
N.A.
52.9
N.A.
N.A.
N.A.
N.A.
51.6
P-Site Identity:
100
100
73.3
73.3
N.A.
66.6
6.6
N.A.
66.6
73.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
80
P-Site Similarity:
100
100
80
80
N.A.
86.6
33.3
N.A.
80
86.6
N.A.
80
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
90
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% D
% Glu:
0
0
0
10
40
0
0
0
0
90
0
0
10
40
80
% E
% Phe:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
20
0
0
0
0
0
0
90
0
0
10
0
% G
% His:
0
0
0
20
0
0
0
10
0
0
0
0
0
10
0
% H
% Ile:
0
80
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
80
0
10
0
0
0
0
20
0
% K
% Leu:
0
0
0
10
30
0
0
0
0
0
0
0
10
10
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
10
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
70
0
0
0
20
0
0
% P
% Gln:
0
0
0
0
20
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
20
10
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
80
30
0
0
% S
% Thr:
0
0
90
0
10
0
0
0
10
0
0
10
0
0
10
% T
% Val:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
30
0
90
0
60
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _