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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CX3CR1
All Species:
11.21
Human Site:
S336
Identified Species:
35.24
UniProt:
P49238
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49238
NP_001328.1
355
40396
S336
S
Q
R
S
R
H
G
S
V
L
S
S
N
F
T
Chimpanzee
Pan troglodytes
NP_001139725
355
40286
S336
S
Q
R
S
R
H
G
S
V
L
S
S
N
F
T
Rhesus Macaque
Macaca mulatta
O18793
360
41121
V340
P
V
F
Y
R
E
T
V
D
G
V
T
S
T
N
Dog
Lupus familis
XP_851606
459
52782
S440
S
Q
T
S
R
R
E
S
I
L
S
S
N
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0D9
354
40248
D335
E
S
Q
R
S
R
Q
D
S
I
L
S
S
F
T
Rat
Rattus norvegicus
P35411
354
40309
D335
E
S
Q
R
S
R
Q
D
S
I
L
S
S
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518678
355
40380
S336
V
S
L
S
K
R
E
S
V
I
S
S
N
F
T
Chicken
Gallus gallus
XP_418820
354
40104
M336
S
V
S
Y
A
E
S
M
V
N
S
N
I
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
42.5
65.3
N.A.
82.8
82.2
N.A.
60.8
52.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.5
58.3
71.4
N.A.
90.1
90.4
N.A.
75.2
67.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
73.3
N.A.
20
13.3
N.A.
53.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
80
N.A.
40
33.3
N.A.
66.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
25
13
0
0
0
0
0
0
% D
% Glu:
25
0
0
0
0
25
25
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
13
0
0
0
0
0
0
0
0
0
0
63
0
% F
% Gly:
0
0
0
0
0
0
25
0
0
13
0
0
0
0
0
% G
% His:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
13
38
0
0
13
0
0
% I
% Lys:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
13
0
0
0
0
0
0
38
25
0
0
13
13
% L
% Met:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
13
0
13
50
0
13
% N
% Pro:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
38
25
0
0
0
25
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
25
25
50
50
0
0
0
0
0
0
0
0
0
% R
% Ser:
50
38
13
50
25
0
13
50
25
0
63
75
38
0
0
% S
% Thr:
0
0
13
0
0
0
13
0
0
0
0
13
0
25
75
% T
% Val:
13
25
0
0
0
0
0
13
50
0
13
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _