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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPIA
All Species:
15.15
Human Site:
S49
Identified Species:
22.22
UniProt:
P49247
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49247
NP_653164.2
311
33269
S49
R
L
P
G
R
A
Q
S
G
T
R
G
G
A
G
Chimpanzee
Pan troglodytes
XP_525809
311
33223
S49
R
L
P
G
R
A
Q
S
G
T
R
G
G
A
G
Rhesus Macaque
Macaca mulatta
XP_001094618
237
26073
G31
Q
V
L
G
I
G
S
G
S
T
I
V
H
A
V
Dog
Lupus familis
XP_532963
216
23897
G10
Q
V
L
G
I
G
S
G
S
T
I
V
H
A
V
Cat
Felis silvestris
Mouse
Mus musculus
P47968
303
32432
S49
Q
L
P
G
R
A
H
S
E
T
R
G
D
K
G
Rat
Rattus norvegicus
NP_001102102
303
32453
S49
Q
L
P
G
R
T
Q
S
E
T
R
G
D
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512073
369
40688
A105
V
E
E
D
W
S
R
A
G
G
G
A
P
S
W
Chicken
Gallus gallus
NP_001026341
235
25628
G29
Q
V
L
G
I
G
S
G
S
T
I
V
H
A
V
Frog
Xenopus laevis
NP_001084550
235
25660
G29
Q
A
L
G
I
G
S
G
S
T
I
V
H
A
V
Zebra Danio
Brachydanio rerio
NP_001007290
275
30361
L48
M
A
E
E
A
K
K
L
A
A
Y
A
A
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726309
241
26516
S35
I
L
G
I
G
S
G
S
T
V
V
Y
A
V
Q
Honey Bee
Apis mellifera
XP_623160
237
26131
I31
K
N
N
S
I
I
G
I
G
S
G
S
T
V
I
Nematode Worm
Caenorhab. elegans
P41994
251
27203
K45
V
G
S
G
S
T
V
K
Y
L
V
E
Y
L
K
Sea Urchin
Strong. purpuratus
XP_781272
280
30865
A50
D
Q
A
K
K
A
A
A
C
A
A
V
N
N
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZU38
265
28498
S50
K
A
V
E
F
V
E
S
G
M
V
L
G
L
G
Baker's Yeast
Sacchar. cerevisiae
Q12189
258
28240
S48
I
I
G
I
G
S
G
S
T
V
V
Y
V
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
76.2
68.1
N.A.
89.3
89
N.A.
58.2
61.7
60.1
61.7
N.A.
46.2
47.9
36
44.3
Protein Similarity:
100
100
76.2
69.1
N.A.
93.2
92.9
N.A.
66.6
70.7
67.8
72.6
N.A.
59.8
63.3
52
55.9
P-Site Identity:
100
100
20
20
N.A.
66.6
66.6
N.A.
6.6
20
20
0
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
100
33.3
33.3
N.A.
73.3
73.3
N.A.
33.3
33.3
26.6
6.6
N.A.
20
20
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.4
36.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.4
51.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
7
0
7
25
7
13
7
13
7
13
13
44
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
0
0
0
0
0
0
0
0
13
0
7
% D
% Glu:
0
7
13
13
0
0
7
0
13
0
0
7
0
0
7
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
13
57
13
25
19
25
32
7
13
25
19
0
32
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
25
0
7
% H
% Ile:
13
7
0
13
32
7
0
7
0
0
25
0
0
0
7
% I
% Lys:
13
0
0
7
7
7
7
7
0
0
0
0
0
13
7
% K
% Leu:
0
32
25
0
0
0
0
7
0
7
0
7
0
13
0
% L
% Met:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
7
7
0
0
0
0
0
0
0
0
0
7
7
0
% N
% Pro:
0
0
25
0
0
0
0
0
0
0
0
0
7
0
0
% P
% Gln:
38
7
0
0
0
0
19
0
0
0
0
0
0
0
7
% Q
% Arg:
13
0
0
0
25
0
7
0
0
0
25
0
0
0
0
% R
% Ser:
0
0
7
7
7
19
25
44
25
7
0
7
0
7
0
% S
% Thr:
0
0
0
0
0
13
0
0
13
50
0
0
7
0
0
% T
% Val:
13
19
7
0
0
7
7
0
0
13
25
32
7
19
25
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
7
13
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _