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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPIA
All Species:
4.55
Human Site:
S65
Identified Species:
6.67
UniProt:
P49247
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49247
NP_653164.2
311
33269
S65
T
S
T
S
C
G
D
S
N
S
I
C
P
A
P
Chimpanzee
Pan troglodytes
XP_525809
311
33223
S65
T
S
T
S
C
G
D
S
S
S
I
C
P
A
P
Rhesus Macaque
Macaca mulatta
XP_001094618
237
26073
Q47
R
I
A
E
R
V
K
Q
E
N
L
N
L
V
C
Dog
Lupus familis
XP_532963
216
23897
Q26
R
I
A
E
R
V
K
Q
E
N
L
N
L
V
C
Cat
Felis silvestris
Mouse
Mus musculus
P47968
303
32432
P65
S
S
A
G
G
P
A
P
S
T
M
S
K
A
E
Rat
Rattus norvegicus
NP_001102102
303
32453
P65
S
S
A
G
G
P
A
P
S
T
M
S
K
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512073
369
40688
L121
Q
A
A
S
L
R
E
L
G
R
S
S
P
R
P
Chicken
Gallus gallus
NP_001026341
235
25628
Q45
R
L
A
E
R
V
K
Q
E
N
L
S
I
V
C
Frog
Xenopus laevis
NP_001084550
235
25660
Q45
R
L
A
E
R
V
K
Q
E
N
L
K
V
V
C
Zebra Danio
Brachydanio rerio
NP_001007290
275
30361
I64
H
I
Q
N
N
Q
V
I
G
V
G
S
G
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726309
241
26516
E51
I
A
E
R
V
W
K
E
G
E
L
T
D
L
I
Honey Bee
Apis mellifera
XP_623160
237
26131
R47
A
V
H
R
L
V
E
R
V
K
E
E
N
L
N
Nematode Worm
Caenorhab. elegans
P41994
251
27203
K61
G
F
Q
N
G
S
L
K
D
I
I
C
V
P
T
Sea Urchin
Strong. purpuratus
XP_781272
280
30865
V66
K
D
H
C
R
L
G
V
G
S
G
S
T
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZU38
265
28498
V66
G
S
T
A
K
H
A
V
D
R
I
G
E
L
L
Baker's Yeast
Sacchar. cerevisiae
Q12189
258
28240
P64
I
G
Q
Y
L
H
D
P
K
F
Y
E
V
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
76.2
68.1
N.A.
89.3
89
N.A.
58.2
61.7
60.1
61.7
N.A.
46.2
47.9
36
44.3
Protein Similarity:
100
100
76.2
69.1
N.A.
93.2
92.9
N.A.
66.6
70.7
67.8
72.6
N.A.
59.8
63.3
52
55.9
P-Site Identity:
100
93.3
0
0
N.A.
13.3
13.3
N.A.
20
0
0
0
N.A.
0
0
13.3
6.6
P-Site Similarity:
100
100
13.3
13.3
N.A.
40
40
N.A.
33.3
13.3
13.3
13.3
N.A.
13.3
6.6
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.4
36.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.4
51.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
13
44
7
0
0
19
0
0
0
0
0
0
32
0
% A
% Cys:
0
0
0
7
13
0
0
0
0
0
0
19
0
0
25
% C
% Asp:
0
7
0
0
0
0
19
0
13
0
0
0
7
0
0
% D
% Glu:
0
0
7
25
0
0
13
7
25
7
7
13
7
0
13
% E
% Phe:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
13
7
0
13
19
13
7
0
25
0
13
7
7
0
0
% G
% His:
7
0
13
0
0
13
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
19
0
0
0
0
0
7
0
7
25
0
7
7
7
% I
% Lys:
7
0
0
0
7
0
32
7
7
7
0
7
13
0
0
% K
% Leu:
0
13
0
0
19
7
7
7
0
0
32
0
13
19
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
0
0
0
13
7
0
0
0
7
25
0
13
7
0
7
% N
% Pro:
0
0
0
0
0
13
0
19
0
0
0
0
19
7
19
% P
% Gln:
7
0
19
0
0
7
0
25
0
0
0
0
0
0
0
% Q
% Arg:
25
0
0
13
32
7
0
7
0
13
0
0
0
7
0
% R
% Ser:
13
32
0
19
0
7
0
13
19
19
7
38
0
7
7
% S
% Thr:
13
0
19
0
0
0
0
0
0
13
0
7
7
0
13
% T
% Val:
0
7
0
0
7
32
7
13
7
7
0
0
19
25
7
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _