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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPIA
All Species:
24.85
Human Site:
Y295
Identified Species:
36.44
UniProt:
P49247
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49247
NP_653164.2
311
33269
Y295
I
N
M
A
E
R
V
Y
F
G
M
Q
D
G
S
Chimpanzee
Pan troglodytes
XP_525809
311
33223
Y295
I
N
M
A
E
R
V
Y
F
G
M
Q
D
G
S
Rhesus Macaque
Macaca mulatta
XP_001094618
237
26073
G223
M
A
E
R
V
Y
F
G
M
Q
D
G
S
V
N
Dog
Lupus familis
XP_532963
216
23897
G202
M
A
E
R
V
Y
F
G
M
Q
D
G
S
V
N
Cat
Felis silvestris
Mouse
Mus musculus
P47968
303
32432
Y288
I
N
M
A
E
R
V
Y
F
G
M
Q
D
G
S
Rat
Rattus norvegicus
NP_001102102
303
32453
Y288
I
N
M
A
E
R
V
Y
F
G
M
Q
D
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512073
369
40688
Y353
I
D
M
A
E
R
V
Y
F
G
M
E
D
G
S
Chicken
Gallus gallus
NP_001026341
235
25628
G221
M
A
E
V
V
Y
F
G
M
E
D
G
S
V
S
Frog
Xenopus laevis
NP_001084550
235
25660
G221
M
A
E
R
V
Y
F
G
M
E
D
G
T
V
T
Zebra Danio
Brachydanio rerio
NP_001007290
275
30361
Y259
V
G
M
A
E
R
V
Y
F
G
M
E
D
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726309
241
26516
C227
F
V
N
M
A
H
K
C
Y
Y
G
M
A
N
G
Honey Bee
Apis mellifera
XP_623160
237
26131
K223
L
F
I
K
M
A
K
K
V
Y
F
G
M
P
D
Nematode Worm
Caenorhab. elegans
P41994
251
27203
Y237
V
D
A
V
F
F
A
Y
S
D
G
S
V
K
E
Sea Urchin
Strong. purpuratus
XP_781272
280
30865
A266
F
I
N
M
A
K
R
A
Y
F
G
M
A
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZU38
265
28498
S249
G
M
F
L
D
M
A
S
T
V
I
I
A
G
E
Baker's Yeast
Sacchar. cerevisiae
Q12189
258
28240
S242
G
L
F
I
D
N
A
S
K
A
Y
F
G
N
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
76.2
68.1
N.A.
89.3
89
N.A.
58.2
61.7
60.1
61.7
N.A.
46.2
47.9
36
44.3
Protein Similarity:
100
100
76.2
69.1
N.A.
93.2
92.9
N.A.
66.6
70.7
67.8
72.6
N.A.
59.8
63.3
52
55.9
P-Site Identity:
100
100
0
0
N.A.
100
100
N.A.
86.6
6.6
0
80
N.A.
0
0
6.6
0
P-Site Similarity:
100
100
13.3
13.3
N.A.
100
100
N.A.
100
13.3
13.3
93.3
N.A.
6.6
13.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.4
36.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.4
51.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
7
38
13
7
19
7
0
7
0
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
13
0
0
0
0
7
25
0
38
7
7
% D
% Glu:
0
0
25
0
38
0
0
0
0
13
0
13
0
0
13
% E
% Phe:
13
7
13
0
7
7
25
0
38
7
7
7
0
0
0
% F
% Gly:
13
7
0
0
0
0
0
25
0
38
19
32
7
44
13
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
32
7
7
7
0
0
0
0
0
0
7
7
0
0
0
% I
% Lys:
0
0
0
7
0
7
13
7
7
0
0
0
0
7
0
% K
% Leu:
7
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
25
7
38
13
7
7
0
0
25
0
38
13
7
0
0
% M
% Asn:
0
25
13
0
0
7
0
0
0
0
0
0
0
13
13
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
13
0
25
0
0
0
% Q
% Arg:
0
0
0
19
0
38
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
13
7
0
0
7
19
0
50
% S
% Thr:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
7
% T
% Val:
13
7
0
13
25
0
38
0
7
7
0
0
7
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
25
0
44
13
13
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _