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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LMAN1
All Species:
35.45
Human Site:
Y227
Identified Species:
70.91
UniProt:
P49257
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49257
NP_005561.1
510
57549
Y227
F
T
P
D
K
N
D
Y
E
F
C
A
K
V
E
Chimpanzee
Pan troglodytes
XP_001143039
510
57514
Y227
F
T
P
D
K
N
D
Y
E
F
C
A
K
V
E
Rhesus Macaque
Macaca mulatta
XP_001088053
510
57339
Y227
F
T
P
D
K
N
D
Y
E
F
C
A
K
V
E
Dog
Lupus familis
XP_533390
518
58041
Y235
F
T
P
D
K
N
D
Y
E
F
C
A
K
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0F3
517
57770
Y235
F
T
P
D
K
N
D
Y
E
F
C
A
K
V
E
Rat
Rattus norvegicus
Q62902
517
57939
Y235
F
T
P
D
K
N
D
Y
E
F
C
A
K
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516403
344
39024
L124
N
D
G
A
N
Q
A
L
A
S
C
Q
R
D
F
Chicken
Gallus gallus
NP_001026570
503
56501
Y220
F
T
P
D
K
E
D
Y
E
F
C
A
K
V
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524776
512
57550
Y217
M
S
N
N
N
D
D
Y
E
L
C
L
R
A
D
Honey Bee
Apis mellifera
XP_623191
502
57570
Y212
M
T
N
N
E
Q
D
Y
E
T
C
F
Q
V
E
Nematode Worm
Caenorhab. elegans
NP_492548
492
54959
E210
M
Q
P
T
P
R
Y
E
L
C
M
R
A
E
N
Sea Urchin
Strong. purpuratus
XP_780803
509
57721
Y211
L
S
A
N
D
H
D
Y
E
L
C
M
R
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.6
89.5
N.A.
88
88.1
N.A.
58.6
78.6
N.A.
N.A.
N.A.
43.1
43.3
35.8
43.1
Protein Similarity:
100
99.4
97.4
94
N.A.
93.8
94.3
N.A.
62.9
88.8
N.A.
N.A.
N.A.
63.4
65
57
63.9
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
93.3
N.A.
N.A.
N.A.
26.6
46.6
6.6
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
93.3
N.A.
N.A.
N.A.
60
66.6
6.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
0
9
0
9
0
0
59
9
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
92
0
0
0
0
% C
% Asp:
0
9
0
59
9
9
84
0
0
0
0
0
0
9
9
% D
% Glu:
0
0
0
0
9
9
0
9
84
0
0
0
0
9
75
% E
% Phe:
59
0
0
0
0
0
0
0
0
59
0
9
0
0
9
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
59
0
0
0
0
0
0
0
59
0
0
% K
% Leu:
9
0
0
0
0
0
0
9
9
17
0
9
0
9
0
% L
% Met:
25
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% M
% Asn:
9
0
17
25
17
50
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
67
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
17
0
0
0
0
0
9
9
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
9
25
0
0
% R
% Ser:
0
17
0
0
0
0
0
0
0
9
0
0
0
0
0
% S
% Thr:
0
67
0
9
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
59
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _