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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC11A1
All Species:
16.06
Human Site:
S54
Identified Species:
27.18
UniProt:
P49279
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49279
NP_000569.3
550
59872
S54
D
T
K
P
G
T
F
S
L
R
K
L
W
A
F
Chimpanzee
Pan troglodytes
XP_001156701
550
59885
S54
D
T
K
P
G
T
F
S
L
R
K
L
W
A
F
Rhesus Macaque
Macaca mulatta
XP_001089328
517
56557
P47
I
P
I
P
D
T
K
P
G
T
F
S
L
R
K
Dog
Lupus familis
XP_543669
756
83237
S261
E
E
E
Y
S
C
F
S
F
R
K
L
W
A
F
Cat
Felis silvestris
Mouse
Mus musculus
P41251
548
59665
K54
Q
G
T
F
S
L
R
K
L
W
A
F
T
G
P
Rat
Rattus norvegicus
P70553
507
55903
L36
E
P
S
R
N
T
Y
L
S
E
K
I
P
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519823
464
50915
Chicken
Gallus gallus
P51027
555
60948
S59
K
G
S
T
P
G
F
S
F
R
K
L
W
A
F
Frog
Xenopus laevis
NP_001088008
550
60993
W55
G
F
S
F
R
K
L
W
A
F
T
G
P
G
F
Zebra Danio
Brachydanio rerio
NP_001035460
547
60061
K56
E
K
L
F
S
F
R
K
L
W
A
F
T
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49283
596
65448
S73
D
S
T
N
V
G
F
S
F
R
K
L
W
A
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21434
562
63085
K55
E
K
A
F
S
F
K
K
L
W
A
F
T
G
P
Sea Urchin
Strong. purpuratus
XP_781841
611
67695
S98
D
Q
E
N
Y
A
F
S
F
R
K
L
W
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SNV9
509
56119
L39
R
N
E
E
E
D
D
L
E
H
G
V
G
C
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
91.6
48.2
N.A.
87.4
80.7
N.A.
58.7
67.7
65.6
64.1
N.A.
51.3
N.A.
46.9
53.3
Protein Similarity:
100
99.6
92.7
59.1
N.A.
91.6
85
N.A.
71.6
78.9
78.7
76.3
N.A.
65.9
N.A.
64.4
67.1
P-Site Identity:
100
100
13.3
53.3
N.A.
6.6
13.3
N.A.
0
53.3
6.6
6.6
N.A.
60
N.A.
6.6
60
P-Site Similarity:
100
100
13.3
66.6
N.A.
6.6
33.3
N.A.
0
53.3
6.6
13.3
N.A.
66.6
N.A.
13.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
0
8
0
22
0
0
43
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% C
% Asp:
29
0
0
0
8
8
8
0
0
0
0
0
0
0
0
% D
% Glu:
29
8
22
8
8
0
0
0
8
8
0
0
0
0
0
% E
% Phe:
0
8
0
29
0
15
43
0
29
8
8
22
0
0
50
% F
% Gly:
8
15
0
0
15
15
0
0
8
0
8
8
8
29
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
0
0
0
0
8
0
8
0
% I
% Lys:
8
15
15
0
0
8
15
22
0
0
50
0
0
0
8
% K
% Leu:
0
0
8
0
0
8
8
15
36
0
0
43
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
15
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
15
0
22
8
0
0
8
0
0
0
0
15
0
29
% P
% Gln:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
8
8
0
15
0
0
43
0
0
0
8
0
% R
% Ser:
0
8
22
0
29
0
0
43
8
0
0
8
0
0
0
% S
% Thr:
0
15
15
8
0
29
0
0
0
8
8
0
22
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
22
0
0
43
0
0
% W
% Tyr:
0
0
0
8
8
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _