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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC11A2
All Species:
16.97
Human Site:
S23
Identified Species:
28.72
UniProt:
P49281
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49281
NP_000608.1
568
62266
S23
G
D
H
G
E
S
A
S
L
G
N
I
N
P
A
Chimpanzee
Pan troglodytes
XP_509061
568
62257
S23
G
D
H
G
E
S
A
S
L
G
N
I
N
P
A
Rhesus Macaque
Macaca mulatta
XP_001082702
568
62226
C23
G
D
H
G
E
S
A
C
L
G
T
V
N
P
V
Dog
Lupus familis
XP_543669
756
83237
S218
G
D
H
G
D
S
P
S
L
G
T
L
N
P
A
Cat
Felis silvestris
Mouse
Mus musculus
P49282
568
62349
S23
G
D
H
G
D
S
A
S
L
G
A
I
N
P
A
Rat
Rattus norvegicus
O54902
568
62258
S23
G
D
H
G
D
S
A
S
L
G
A
I
N
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519823
464
50915
Chicken
Gallus gallus
P51027
555
60948
G22
L
A
G
S
L
N
R
G
Q
T
D
A
S
N
V
Frog
Xenopus laevis
NP_001088008
550
60993
D21
R
S
Y
G
T
I
G
D
P
E
T
C
T
K
E
Zebra Danio
Brachydanio rerio
NP_001035460
547
60061
Y21
V
P
Q
E
P
D
L
Y
S
P
V
S
P
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49283
596
65448
R30
A
S
G
G
G
S
Q
R
S
N
Q
L
H
H
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21434
562
63085
Q21
A
E
P
W
R
I
T
Q
N
D
H
L
E
Q
D
Sea Urchin
Strong. purpuratus
XP_781841
611
67695
L55
L
E
P
S
Q
S
S
L
D
T
G
V
V
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FN18
512
56367
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.7
66
N.A.
91.7
91.7
N.A.
74.1
61
63.2
72.5
N.A.
53.1
N.A.
51.4
56.4
Protein Similarity:
100
99.8
98.7
70.3
N.A.
95.7
96.1
N.A.
79
75.8
76
81.8
N.A.
67.4
N.A.
69.5
69.5
P-Site Identity:
100
100
73.3
73.3
N.A.
86.6
86.6
N.A.
0
0
6.6
0
N.A.
13.3
N.A.
0
6.6
P-Site Similarity:
100
100
80
86.6
N.A.
93.3
93.3
N.A.
0
20
13.3
0
N.A.
26.6
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
0
0
0
36
0
0
0
15
8
0
0
36
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% C
% Asp:
0
43
0
0
22
8
0
8
8
8
8
0
0
8
8
% D
% Glu:
0
15
0
8
22
0
0
0
0
8
0
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
43
0
15
58
8
0
8
8
0
43
8
0
0
0
0
% G
% His:
0
0
43
0
0
0
0
0
0
0
8
0
8
8
0
% H
% Ile:
0
0
0
0
0
15
0
0
0
0
0
29
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
15
0
0
0
8
0
8
8
43
0
0
22
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
8
8
15
0
43
8
0
% N
% Pro:
0
8
15
0
8
0
8
0
8
8
0
0
8
43
15
% P
% Gln:
0
0
8
0
8
0
8
8
8
0
8
0
0
8
8
% Q
% Arg:
8
0
0
0
8
0
8
8
0
0
0
0
0
0
0
% R
% Ser:
0
15
0
15
0
58
8
36
15
0
0
8
8
0
0
% S
% Thr:
0
0
0
0
8
0
8
0
0
15
22
0
8
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
8
15
8
8
15
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _