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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC11A2
All Species:
44.24
Human Site:
S278
Identified Species:
74.87
UniProt:
P49281
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49281
NP_000608.1
568
62266
S278
L
H
S
A
L
V
K
S
R
Q
V
N
R
N
N
Chimpanzee
Pan troglodytes
XP_509061
568
62257
S278
L
H
S
A
L
V
K
S
R
Q
V
N
R
N
N
Rhesus Macaque
Macaca mulatta
XP_001082702
568
62226
S278
L
H
S
A
L
V
K
S
R
Q
V
N
R
N
N
Dog
Lupus familis
XP_543669
756
83237
S473
L
H
S
A
L
V
K
S
R
Q
I
N
R
A
N
Cat
Felis silvestris
Mouse
Mus musculus
P49282
568
62349
S278
L
H
S
A
L
V
K
S
R
Q
V
N
R
A
N
Rat
Rattus norvegicus
O54902
568
62258
S278
L
H
S
A
L
V
K
S
R
Q
V
N
R
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519823
464
50915
S183
L
R
G
L
F
V
P
S
C
Q
G
C
K
T
R
Chicken
Gallus gallus
P51027
555
60948
T271
L
H
S
S
L
V
K
T
R
A
I
D
R
S
K
Frog
Xenopus laevis
NP_001088008
550
60993
M264
S
S
L
V
K
S
R
M
V
D
R
K
Q
K
H
Zebra Danio
Brachydanio rerio
NP_001035460
547
60061
S265
L
H
S
A
L
V
K
S
R
D
I
N
R
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49283
596
65448
S285
L
H
S
A
L
V
K
S
R
D
I
D
R
R
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21434
562
63085
S264
L
H
S
A
L
V
K
S
R
R
V
D
R
K
D
Sea Urchin
Strong. purpuratus
XP_781841
611
67695
S310
L
H
S
A
L
V
K
S
R
D
V
E
R
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FN18
512
56367
T231
V
P
K
L
S
S
R
T
I
K
Q
A
V
G
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.7
66
N.A.
91.7
91.7
N.A.
74.1
61
63.2
72.5
N.A.
53.1
N.A.
51.4
56.4
Protein Similarity:
100
99.8
98.7
70.3
N.A.
95.7
96.1
N.A.
79
75.8
76
81.8
N.A.
67.4
N.A.
69.5
69.5
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
26.6
53.3
0
80
N.A.
66.6
N.A.
73.3
73.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
33.3
86.6
20
93.3
N.A.
80
N.A.
93.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
72
0
0
0
0
0
8
0
8
0
22
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
29
0
22
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
8
0
0
8
0
% G
% His:
0
79
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
29
0
0
0
8
% I
% Lys:
0
0
8
0
8
0
79
0
0
8
0
8
8
15
15
% K
% Leu:
86
0
8
15
79
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
50
0
22
50
% N
% Pro:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
50
8
0
8
0
8
% Q
% Arg:
0
8
0
0
0
0
15
0
79
8
8
0
79
8
8
% R
% Ser:
8
8
79
8
8
15
0
79
0
0
0
0
0
22
0
% S
% Thr:
0
0
0
0
0
0
0
15
0
0
0
0
0
8
0
% T
% Val:
8
0
0
8
0
86
0
0
8
0
50
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _