Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC11A2 All Species: 1.52
Human Site: S37 Identified Species: 2.56
UniProt: P49281 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49281 NP_000608.1 568 62266 S37 A Y S N P S L S Q S P G D S E
Chimpanzee Pan troglodytes XP_509061 568 62257 P37 A Y S N P S L P Q S P G D S E
Rhesus Macaque Macaca mulatta XP_001082702 568 62226 P37 V S S N P S L P R S P G D S E
Dog Lupus familis XP_543669 756 83237 P232 A Y S N S S L P Q S T E H S Q
Cat Felis silvestris
Mouse Mus musculus P49282 568 62349 P37 A Y S N S S L P H S T G D S E
Rat Rattus norvegicus O54902 568 62258 P37 A Y S N S S L P H S T G D S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519823 464 50915
Chicken Gallus gallus P51027 555 60948 P36 V P V P P H H P V P H A Q T Y
Frog Xenopus laevis NP_001088008 550 60993 L35 E K S E R T Y L D E R I A V P
Zebra Danio Brachydanio rerio NP_001035460 547 60061 T35 P Q E E P V S T Y F E E K V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P49283 596 65448 T44 Q Q I L N E T T Y L K P A A K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21434 562 63085 E35 D L L E E D A E S Q E R V D I
Sea Urchin Strong. purpuratus XP_781841 611 67695 Q69 P V L S N G R Q S Q Y E A T A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FN18 512 56367
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.7 66 N.A. 91.7 91.7 N.A. 74.1 61 63.2 72.5 N.A. 53.1 N.A. 51.4 56.4
Protein Similarity: 100 99.8 98.7 70.3 N.A. 95.7 96.1 N.A. 79 75.8 76 81.8 N.A. 67.4 N.A. 69.5 69.5
P-Site Identity: 100 93.3 73.3 60 N.A. 73.3 73.3 N.A. 0 6.6 6.6 6.6 N.A. 0 N.A. 0 0
P-Site Similarity: 100 93.3 80 66.6 N.A. 73.3 73.3 N.A. 0 13.3 13.3 13.3 N.A. 20 N.A. 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. 45.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 62.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 36 0 0 0 0 0 8 0 0 0 0 8 22 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 8 0 0 8 0 0 0 36 8 0 % D
% Glu: 8 0 8 22 8 8 0 8 0 8 15 22 0 0 36 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 0 0 0 36 0 0 0 % G
% His: 0 0 0 0 0 8 8 0 15 0 8 0 8 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 8 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 8 0 8 0 8 % K
% Leu: 0 8 15 8 0 0 43 8 0 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 43 15 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 15 8 0 8 36 0 0 43 0 8 22 8 0 0 15 % P
% Gln: 8 15 0 0 0 0 0 8 22 15 0 0 8 0 8 % Q
% Arg: 0 0 0 0 8 0 8 0 8 0 8 8 0 0 0 % R
% Ser: 0 8 50 8 22 43 8 8 15 43 0 0 0 43 0 % S
% Thr: 0 0 0 0 0 8 8 15 0 0 22 0 0 15 0 % T
% Val: 15 8 8 0 0 8 0 0 8 0 0 0 8 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 36 0 0 0 0 8 0 15 0 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _