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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC11A2
All Species:
18.79
Human Site:
S43
Identified Species:
31.79
UniProt:
P49281
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49281
NP_000608.1
568
62266
S43
L
S
Q
S
P
G
D
S
E
E
Y
F
A
T
Y
Chimpanzee
Pan troglodytes
XP_509061
568
62257
S43
L
P
Q
S
P
G
D
S
E
E
Y
F
A
T
Y
Rhesus Macaque
Macaca mulatta
XP_001082702
568
62226
S43
L
P
R
S
P
G
D
S
E
E
Y
F
A
T
Y
Dog
Lupus familis
XP_543669
756
83237
S238
L
P
Q
S
T
E
H
S
Q
E
P
F
T
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
P49282
568
62349
S43
L
P
H
S
T
G
D
S
E
E
P
F
T
T
Y
Rat
Rattus norvegicus
O54902
568
62258
S43
L
P
H
S
T
G
D
S
E
E
P
F
T
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519823
464
50915
Chicken
Gallus gallus
P51027
555
60948
T42
H
P
V
P
H
A
Q
T
Y
L
D
E
L
I
S
Frog
Xenopus laevis
NP_001088008
550
60993
V41
Y
L
D
E
R
I
A
V
P
S
T
S
M
P
G
Zebra Danio
Brachydanio rerio
NP_001035460
547
60061
V41
S
T
Y
F
E
E
K
V
P
I
P
D
D
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49283
596
65448
A50
T
T
Y
L
K
P
A
A
K
Q
A
Y
F
S
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21434
562
63085
D41
A
E
S
Q
E
R
V
D
I
P
V
D
D
V
E
Sea Urchin
Strong. purpuratus
XP_781841
611
67695
T75
R
Q
S
Q
Y
E
A
T
A
D
N
G
G
T
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FN18
512
56367
R8
M
S
E
T
D
R
E
R
P
L
L
A
S
E
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.7
66
N.A.
91.7
91.7
N.A.
74.1
61
63.2
72.5
N.A.
53.1
N.A.
51.4
56.4
Protein Similarity:
100
99.8
98.7
70.3
N.A.
95.7
96.1
N.A.
79
75.8
76
81.8
N.A.
67.4
N.A.
69.5
69.5
P-Site Identity:
100
93.3
86.6
53.3
N.A.
66.6
66.6
N.A.
0
0
0
0
N.A.
0
N.A.
0
13.3
P-Site Similarity:
100
93.3
93.3
60
N.A.
66.6
66.6
N.A.
0
6.6
0
6.6
N.A.
40
N.A.
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
22
8
8
0
8
8
22
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
36
8
0
8
8
15
15
0
8
% D
% Glu:
0
8
8
8
15
22
8
0
36
43
0
8
0
8
15
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
43
8
0
0
% F
% Gly:
0
0
0
0
0
36
0
0
0
0
0
8
8
8
8
% G
% His:
8
0
15
0
8
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
8
8
0
0
0
8
0
% I
% Lys:
0
0
0
0
8
0
8
0
8
0
0
0
0
0
0
% K
% Leu:
43
8
0
8
0
0
0
0
0
15
8
0
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
43
0
8
22
8
0
0
22
8
29
0
0
8
0
% P
% Gln:
0
8
22
15
0
0
8
0
8
8
0
0
0
0
0
% Q
% Arg:
8
0
8
0
8
15
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
15
15
43
0
0
0
43
0
8
0
8
8
8
8
% S
% Thr:
8
15
0
8
22
0
0
15
0
0
8
0
22
50
8
% T
% Val:
0
0
8
0
0
0
8
15
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
15
0
8
0
0
0
8
0
22
8
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _