KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC11A2
All Species:
22.73
Human Site:
T228
Identified Species:
38.46
UniProt:
P49281
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49281
NP_000608.1
568
62266
T228
T
F
G
Y
E
Y
V
T
V
K
P
S
Q
S
Q
Chimpanzee
Pan troglodytes
XP_509061
568
62257
T228
T
F
G
Y
E
Y
V
T
V
K
P
S
Q
S
Q
Rhesus Macaque
Macaca mulatta
XP_001082702
568
62226
T228
T
F
G
Y
E
Y
V
T
V
K
P
S
Q
S
Q
Dog
Lupus familis
XP_543669
756
83237
T423
T
F
G
Y
E
Y
V
T
V
K
P
S
Q
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
P49282
568
62349
T228
T
F
G
Y
E
Y
I
T
V
K
P
S
Q
S
Q
Rat
Rattus norvegicus
O54902
568
62258
T228
T
F
G
Y
E
Y
V
T
V
K
P
S
Q
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519823
464
50915
F137
A
D
T
F
V
F
L
F
L
D
K
Y
G
L
R
Chicken
Gallus gallus
P51027
555
60948
M221
T
F
G
Y
E
Y
V
M
V
R
P
A
Q
T
E
Frog
Xenopus laevis
NP_001088008
550
60993
E219
V
V
K
P
D
Q
K
E
V
L
K
G
M
F
F
Zebra Danio
Brachydanio rerio
NP_001035460
547
60061
Q220
Y
V
R
V
A
P
D
Q
A
A
V
L
Q
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49283
596
65448
V235
S
F
G
Y
E
Y
I
V
S
A
P
N
Q
G
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21434
562
63085
I219
F
V
V
V
K
P
P
I
G
E
V
I
S
G
M
Sea Urchin
Strong. purpuratus
XP_781841
611
67695
A260
T
F
G
Y
E
Y
V
A
A
A
P
D
Q
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FN18
512
56367
I186
L
F
L
E
N
Y
G
I
R
K
L
E
A
V
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.7
66
N.A.
91.7
91.7
N.A.
74.1
61
63.2
72.5
N.A.
53.1
N.A.
51.4
56.4
Protein Similarity:
100
99.8
98.7
70.3
N.A.
95.7
96.1
N.A.
79
75.8
76
81.8
N.A.
67.4
N.A.
69.5
69.5
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
0
66.6
6.6
6.6
N.A.
46.6
N.A.
0
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
93.3
13.3
6.6
N.A.
73.3
N.A.
13.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
8
15
22
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
8
0
0
8
0
8
0
0
0
% D
% Glu:
0
0
0
8
65
0
0
8
0
8
0
8
0
0
15
% E
% Phe:
8
72
0
8
0
8
0
8
0
0
0
0
0
8
15
% F
% Gly:
0
0
65
0
0
0
8
0
8
0
0
8
8
29
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
15
15
0
0
0
8
0
0
0
% I
% Lys:
0
0
8
0
8
0
8
0
0
50
15
0
0
0
0
% K
% Leu:
8
0
8
0
0
0
8
0
8
8
8
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
15
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
8
0
15
8
0
0
0
65
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
8
0
0
0
0
72
0
50
% Q
% Arg:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
8
% R
% Ser:
8
0
0
0
0
0
0
0
8
0
0
43
8
43
0
% S
% Thr:
58
0
8
0
0
0
0
43
0
0
0
0
0
8
0
% T
% Val:
8
22
8
15
8
0
50
8
58
0
15
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
65
0
72
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _