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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC11A2
All Species:
10.3
Human Site:
T335
Identified Species:
17.44
UniProt:
P49281
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49281
NP_000608.1
568
62266
T335
E
Q
V
V
E
V
C
T
N
T
S
S
P
H
A
Chimpanzee
Pan troglodytes
XP_509061
568
62257
T335
E
Q
V
V
E
V
C
T
N
T
S
S
P
H
A
Rhesus Macaque
Macaca mulatta
XP_001082702
568
62226
T335
E
Q
V
V
E
V
C
T
N
T
S
S
P
H
A
Dog
Lupus familis
XP_543669
756
83237
R530
D
Q
V
V
A
V
C
R
N
S
S
S
P
H
S
Cat
Felis silvestris
Mouse
Mus musculus
P49282
568
62349
K335
K
Q
V
V
E
V
C
K
N
N
S
S
P
H
A
Rat
Rattus norvegicus
O54902
568
62258
R335
E
Q
V
V
E
V
C
R
N
S
S
S
P
H
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519823
464
50915
E238
A
N
K
Y
F
F
I
E
S
C
I
A
L
F
V
Chicken
Gallus gallus
P51027
555
60948
N329
D
V
H
N
K
C
V
N
S
S
V
S
R
Y
A
Frog
Xenopus laevis
NP_001088008
550
60993
Q319
Q
D
A
F
D
F
C
Q
S
S
S
S
P
H
A
Zebra Danio
Brachydanio rerio
NP_001035460
547
60061
Q320
T
N
M
E
V
S
Q
Q
C
N
E
T
G
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49283
596
65448
Y347
V
C
K
D
K
S
M
Y
E
D
A
K
M
S
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21434
562
63085
A322
D
V
R
E
M
C
I
A
R
H
D
I
P
D
A
Sea Urchin
Strong. purpuratus
XP_781841
611
67695
H369
V
H
N
K
C
V
E
H
N
L
N
M
Y
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FN18
512
56367
S286
S
T
G
A
L
A
V
S
F
I
I
N
V
F
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.7
66
N.A.
91.7
91.7
N.A.
74.1
61
63.2
72.5
N.A.
53.1
N.A.
51.4
56.4
Protein Similarity:
100
99.8
98.7
70.3
N.A.
95.7
96.1
N.A.
79
75.8
76
81.8
N.A.
67.4
N.A.
69.5
69.5
P-Site Identity:
100
100
100
66.6
N.A.
80
86.6
N.A.
0
13.3
40
0
N.A.
0
N.A.
13.3
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
13.3
46.6
66.6
13.3
N.A.
13.3
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
8
0
8
0
0
8
8
0
0
58
% A
% Cys:
0
8
0
0
8
15
50
0
8
8
0
0
0
0
0
% C
% Asp:
22
8
0
8
8
0
0
0
0
8
8
0
0
8
8
% D
% Glu:
29
0
0
15
36
0
8
8
8
0
8
0
0
0
0
% E
% Phe:
0
0
0
8
8
15
0
0
8
0
0
0
0
15
8
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
8
8
0
0
0
0
8
0
8
0
0
0
50
0
% H
% Ile:
0
0
0
0
0
0
15
0
0
8
15
8
0
8
0
% I
% Lys:
8
0
15
8
15
0
0
8
0
0
0
8
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
8
0
0
8
0
0
% L
% Met:
0
0
8
0
8
0
8
0
0
0
0
8
8
0
0
% M
% Asn:
0
15
8
8
0
0
0
8
50
15
8
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
58
0
8
% P
% Gln:
8
43
0
0
0
0
8
15
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
15
8
0
0
0
8
0
0
% R
% Ser:
8
0
0
0
0
15
0
8
22
29
50
58
0
15
8
% S
% Thr:
8
8
0
0
0
0
0
22
0
22
0
8
0
0
0
% T
% Val:
15
15
43
43
8
50
15
0
0
0
8
0
8
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
0
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _