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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTNR1B
All Species:
14.55
Human Site:
S245
Identified Species:
32
UniProt:
P49286
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49286
NP_005950.1
362
40188
S245
S
R
L
C
L
K
P
S
D
L
R
S
F
L
T
Chimpanzee
Pan troglodytes
XP_522146
362
40181
S245
S
R
L
C
L
R
P
S
D
L
R
S
F
L
T
Rhesus Macaque
Macaca mulatta
XP_001084265
362
40249
S245
S
T
L
C
L
R
P
S
D
L
R
S
F
L
T
Dog
Lupus familis
XP_849722
352
39828
I245
P
K
L
R
L
R
P
I
R
F
P
D
F
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIQ6
364
40242
S245
R
K
L
R
L
R
P
S
D
L
R
S
F
L
T
Rat
Rattus norvegicus
P49287
120
14003
F39
V
A
L
V
P
N
F
F
V
G
S
L
E
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512937
349
39010
V243
N
F
L
T
M
F
V
V
F
I
L
F
A
V
C
Chicken
Gallus gallus
P51050
289
32983
A208
A
I
N
P
S
E
M
A
P
K
V
P
E
W
L
Frog
Xenopus laevis
P49219
420
47406
F246
L
R
N
F
L
T
M
F
V
V
F
V
L
F
A
Zebra Danio
Brachydanio rerio
P51049
347
38961
V247
N
F
V
T
M
F
V
V
F
V
L
F
A
I
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P41596
511
56152
S387
H
S
S
P
Y
H
V
S
D
H
K
A
A
V
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
95.5
64.3
N.A.
78.5
26.7
N.A.
57.7
56.9
51.4
63.2
N.A.
23
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
97.5
71.8
N.A.
84
29.5
N.A.
74.8
66
66.1
76.2
N.A.
38.1
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
40
N.A.
73.3
6.6
N.A.
6.6
0
13.3
0
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
53.3
N.A.
86.6
6.6
N.A.
33.3
20
20
33.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
10
0
0
0
10
28
0
10
% A
% Cys:
0
0
0
28
0
0
0
0
0
0
0
0
0
0
19
% C
% Asp:
0
0
0
0
0
0
0
0
46
0
0
10
0
0
10
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
0
19
0
0
% E
% Phe:
0
19
0
10
0
19
10
19
19
10
10
19
46
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
10
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
10
0
10
0
0
0
10
0
% I
% Lys:
0
19
0
0
0
10
0
0
0
10
10
0
0
0
0
% K
% Leu:
10
0
64
0
55
0
0
0
0
37
19
10
10
46
10
% L
% Met:
0
0
0
0
19
0
19
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
19
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
19
10
0
46
0
10
0
10
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
28
0
19
0
37
0
0
10
0
37
0
0
0
0
% R
% Ser:
28
10
10
0
10
0
0
46
0
0
10
37
0
0
0
% S
% Thr:
0
10
0
19
0
10
0
0
0
0
0
0
0
0
55
% T
% Val:
10
0
10
10
0
0
28
19
19
19
10
10
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _