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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NASP
All Species:
21.21
Human Site:
S680
Identified Species:
42.42
UniProt:
P49321
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49321
NP_002473.2
788
85238
S680
T
L
V
E
S
S
T
S
G
F
T
P
G
G
G
Chimpanzee
Pan troglodytes
XP_001158313
788
85189
S680
T
L
V
E
S
S
T
S
G
F
T
P
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001103320
789
86152
S681
T
L
V
E
S
S
T
S
G
F
T
P
S
G
G
Dog
Lupus familis
XP_850471
788
85331
S680
T
L
V
E
S
S
T
S
G
F
T
P
S
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99MD9
773
83935
S666
T
L
V
E
S
S
T
S
G
F
T
P
S
G
A
Rat
Rattus norvegicus
Q66HD3
776
84181
S668
T
L
V
E
S
S
T
S
G
F
T
P
S
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508491
277
30551
K174
T
S
L
S
E
Q
V
K
K
A
E
G
S
S
A
Chicken
Gallus gallus
XP_001235060
721
79054
G605
T
L
V
G
T
T
S
G
F
A
Q
S
E
G
S
Frog
Xenopus laevis
P06180
590
65010
K487
T
V
T
E
K
A
L
K
E
T
L
V
G
G
S
Zebra Danio
Brachydanio rerio
NP_956076
624
68194
T521
A
S
E
A
I
H
Q
T
L
A
G
A
S
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392012
459
50698
D356
I
K
E
P
P
K
T
D
D
S
F
Y
T
V
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791433
387
42939
G284
E
A
G
P
S
A
E
G
D
Q
K
E
D
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
92.4
88.7
N.A.
80.5
80.4
N.A.
29.1
51
43.6
42.6
N.A.
N.A.
27.1
N.A.
24.4
Protein Similarity:
100
99.8
94.5
93.4
N.A.
87.5
87.1
N.A.
32.2
64.2
58.8
58.1
N.A.
N.A.
40.4
N.A.
36.9
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
6.6
26.6
26.6
0
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
13.3
46.6
40
6.6
N.A.
N.A.
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
0
17
0
0
0
25
0
9
0
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
17
0
0
0
9
0
9
% D
% Glu:
9
0
17
59
9
0
9
0
9
0
9
9
9
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
9
50
9
0
0
0
0
% F
% Gly:
0
0
9
9
0
0
0
17
50
0
9
9
25
75
34
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
9
9
0
17
9
0
9
0
0
0
0
% K
% Leu:
0
59
9
0
0
0
9
0
9
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
17
9
0
0
0
0
0
0
50
0
0
0
% P
% Gln:
0
0
0
0
0
9
9
0
0
9
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
17
0
9
59
50
9
50
0
9
0
9
50
9
25
% S
% Thr:
75
0
9
0
9
9
59
9
0
9
50
0
9
9
0
% T
% Val:
0
9
59
0
0
0
9
0
0
0
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _