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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NASP
All Species:
11.82
Human Site:
T404
Identified Species:
23.64
UniProt:
P49321
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49321
NP_002473.2
788
85238
T404
S
I
E
R
L
T
E
T
K
D
G
S
G
L
E
Chimpanzee
Pan troglodytes
XP_001158313
788
85189
T404
S
I
E
R
L
T
E
T
K
D
G
S
G
L
E
Rhesus Macaque
Macaca mulatta
XP_001103320
789
86152
T405
S
I
E
R
L
T
E
T
K
D
G
S
G
L
E
Dog
Lupus familis
XP_850471
788
85331
K404
V
E
E
L
T
E
T
K
D
G
S
G
L
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99MD9
773
83935
E390
T
S
A
E
R
L
T
E
T
K
D
G
S
S
V
Rat
Rattus norvegicus
Q66HD3
776
84181
E392
N
S
A
E
R
L
S
E
T
K
D
G
A
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508491
277
30551
Chicken
Gallus gallus
XP_001235060
721
79054
T345
D
E
S
K
G
M
D
T
S
K
E
P
V
S
A
Frog
Xenopus laevis
P06180
590
65010
S242
E
T
K
E
K
D
L
S
K
E
K
T
D
A
K
Zebra Danio
Brachydanio rerio
NP_956076
624
68194
G276
P
A
S
I
E
K
C
G
N
E
D
E
K
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392012
459
50698
E111
N
I
D
E
K
E
D
E
E
S
E
D
H
T
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791433
387
42939
G39
A
E
A
L
E
L
M
G
Q
G
K
R
N
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
92.4
88.7
N.A.
80.5
80.4
N.A.
29.1
51
43.6
42.6
N.A.
N.A.
27.1
N.A.
24.4
Protein Similarity:
100
99.8
94.5
93.4
N.A.
87.5
87.1
N.A.
32.2
64.2
58.8
58.1
N.A.
N.A.
40.4
N.A.
36.9
P-Site Identity:
100
100
100
13.3
N.A.
0
0
N.A.
0
6.6
6.6
0
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
6.6
6.6
N.A.
0
20
40
13.3
N.A.
N.A.
40
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
25
0
0
0
0
0
0
0
0
0
9
9
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
9
17
0
9
25
25
9
9
0
9
% D
% Glu:
9
25
34
34
17
17
25
25
9
17
17
9
0
9
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
17
0
17
25
25
25
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
34
0
9
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
9
17
9
0
9
34
25
17
0
9
0
17
% K
% Leu:
0
0
0
17
25
25
9
0
0
0
0
0
9
34
0
% L
% Met:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
25
17
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
25
17
17
0
0
0
9
9
9
9
9
25
9
34
0
% S
% Thr:
9
9
0
0
9
25
17
34
17
0
0
9
0
9
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _