KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NASP
All Species:
22.42
Human Site:
T464
Identified Species:
44.85
UniProt:
P49321
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49321
NP_002473.2
788
85238
T464
Q
I
A
A
N
E
E
T
Q
E
R
E
E
Q
M
Chimpanzee
Pan troglodytes
XP_001158313
788
85189
T464
Q
I
A
A
N
E
E
T
Q
E
R
E
E
Q
M
Rhesus Macaque
Macaca mulatta
XP_001103320
789
86152
T465
Q
I
A
A
N
E
E
T
Q
E
R
E
E
Q
M
Dog
Lupus familis
XP_850471
788
85331
T464
K
I
A
A
N
E
E
T
R
E
R
E
E
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
Q99MD9
773
83935
T450
K
I
A
A
N
E
E
T
P
E
R
D
E
Q
M
Rat
Rattus norvegicus
Q66HD3
776
84181
T452
K
I
A
A
N
E
E
T
Q
E
R
D
E
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508491
277
30551
Chicken
Gallus gallus
XP_001235060
721
79054
E405
M
E
E
G
E
E
T
E
E
S
E
E
E
D
K
Frog
Xenopus laevis
P06180
590
65010
E302
M
E
E
E
E
E
G
E
D
S
E
E
N
E
D
Zebra Danio
Brachydanio rerio
NP_956076
624
68194
E336
D
D
D
G
D
E
D
E
D
D
D
D
D
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392012
459
50698
D171
K
V
E
K
S
E
L
D
D
K
T
E
D
N
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791433
387
42939
N99
M
E
N
G
V
L
G
N
A
L
Q
G
V
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
92.4
88.7
N.A.
80.5
80.4
N.A.
29.1
51
43.6
42.6
N.A.
N.A.
27.1
N.A.
24.4
Protein Similarity:
100
99.8
94.5
93.4
N.A.
87.5
87.1
N.A.
32.2
64.2
58.8
58.1
N.A.
N.A.
40.4
N.A.
36.9
P-Site Identity:
100
100
100
86.6
N.A.
80
86.6
N.A.
0
20
13.3
6.6
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
0
26.6
20
46.6
N.A.
N.A.
46.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
50
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
9
0
9
0
9
9
25
9
9
25
17
9
25
% D
% Glu:
0
25
25
9
17
84
50
25
9
50
17
59
59
17
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
25
0
0
17
0
0
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
34
0
0
9
0
0
0
0
0
9
0
0
0
0
17
% K
% Leu:
0
0
0
0
0
9
9
0
0
9
0
0
0
0
0
% L
% Met:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% M
% Asn:
0
0
9
0
50
0
0
9
0
0
0
0
9
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% P
% Gln:
25
0
0
0
0
0
0
0
34
0
9
0
0
50
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
50
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
0
0
0
17
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
50
0
0
9
0
0
0
0
% T
% Val:
0
9
0
0
9
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _