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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FMO5
All Species:
12.42
Human Site:
S508
Identified Species:
27.33
UniProt:
P49326
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49326
NP_001138302.1
533
60221
S508
T
R
V
V
E
R
S
S
S
M
T
S
T
M
T
Chimpanzee
Pan troglodytes
Q8HZ70
535
60885
S508
T
R
A
L
K
D
S
S
N
F
S
V
S
F
L
Rhesus Macaque
Macaca mulatta
Q28505
535
60943
S508
T
R
V
L
K
D
S
S
N
F
P
V
S
F
L
Dog
Lupus familis
XP_536149
535
61210
Q508
T
R
T
L
S
H
D
Q
P
P
Y
S
V
P
F
Cat
Felis silvestris
Mouse
Mus musculus
P97872
533
60011
S508
T
R
V
V
E
R
D
S
S
G
G
S
L
V
T
Rat
Rattus norvegicus
Q8K4C0
533
60037
S508
T
R
V
V
E
R
D
S
S
G
T
S
L
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508066
542
60948
P516
T
G
P
V
R
S
G
P
N
L
S
R
W
P
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083227
537
61630
D508
S
R
V
L
V
D
D
D
M
K
K
H
H
S
V
Zebra Danio
Brachydanio rerio
NP_944592
560
63800
Q509
T
R
C
R
E
E
P
Q
S
Q
S
F
L
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LMA1
530
60378
E508
R
K
S
N
F
L
L
E
A
F
S
P
Y
G
S
Baker's Yeast
Sacchar. cerevisiae
P38866
432
49080
L410
D
K
E
E
R
N
V
L
L
A
E
H
A
Q
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.4
56.6
54.3
N.A.
84
84.2
N.A.
57.5
N.A.
64.9
58.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
77.1
77
73.4
N.A.
93
93
N.A.
75
N.A.
78.7
75.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
33.3
20
N.A.
66.6
73.3
N.A.
13.3
N.A.
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
60
26.6
N.A.
73.3
80
N.A.
40
N.A.
26.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.9
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
10
10
0
0
10
0
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
28
37
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
10
37
10
0
10
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
28
0
10
0
19
10
% F
% Gly:
0
10
0
0
0
0
10
0
0
19
10
0
0
10
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
19
10
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
19
0
0
19
0
0
0
0
10
10
0
0
0
0
% K
% Leu:
0
0
0
37
0
10
10
10
10
10
0
0
28
0
19
% L
% Met:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
0
% M
% Asn:
0
0
0
10
0
10
0
0
28
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
10
10
10
10
10
10
0
19
0
% P
% Gln:
0
0
0
0
0
0
0
19
0
10
0
0
0
10
0
% Q
% Arg:
10
73
0
10
19
28
0
0
0
0
0
10
0
0
0
% R
% Ser:
10
0
10
0
10
10
28
46
37
0
37
37
19
10
28
% S
% Thr:
73
0
10
0
0
0
0
0
0
0
19
0
10
0
28
% T
% Val:
0
0
46
37
10
0
10
0
0
0
0
19
10
19
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _