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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FMO5 All Species: 9.7
Human Site: Y353 Identified Species: 21.33
UniProt: P49326 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49326 NP_001138302.1 533 60221 Y353 V K N K I S L Y K K V F P P N
Chimpanzee Pan troglodytes Q8HZ70 535 60885 L352 V E N N M V S L Y K Y I F P A
Rhesus Macaque Macaca mulatta Q28505 535 60943 L352 V E N N M V S L Y K Y I F P A
Dog Lupus familis XP_536149 535 61210 F353 L D S Q R S M F K F V F P P Q
Cat Felis silvestris
Mouse Mus musculus P97872 533 60011 Y353 V K N K V S L Y K K V F P P N
Rat Rattus norvegicus Q8K4C0 533 60037 Y353 V Q N K V S L Y K K V F P P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508066 542 60948 F361 I D D Q V S L F S R V F P P T
Chicken Gallus gallus
Frog Xenopus laevis NP_001083227 537 61630 L352 A E N N K I P L Y K F V F P P
Zebra Danio Brachydanio rerio NP_944592 560 63800 L353 V S N N K V S L Y K F V Y P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LMA1 530 60378 W355 F K K S S K W W F Y E E G I V
Baker's Yeast Sacchar. cerevisiae P38866 432 49080 Y260 R V L Q N I D Y I I F A T G Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.4 56.6 54.3 N.A. 84 84.2 N.A. 57.5 N.A. 64.9 58.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 77.1 77 73.4 N.A. 93 93 N.A. 75 N.A. 78.7 75.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 26.6 26.6 40 N.A. 93.3 86.6 N.A. 40 N.A. 20 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 40 40 73.3 N.A. 100 100 N.A. 80 N.A. 26.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.1 24.2 N.A.
Protein Similarity: N.A. N.A. N.A. 40.9 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 10 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 28 0 0 0 0 0 0 0 0 10 10 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 19 10 10 28 46 28 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 10 19 0 0 10 10 0 19 0 10 0 % I
% Lys: 0 28 10 28 19 10 0 0 37 64 0 0 0 0 0 % K
% Leu: 10 0 10 0 0 0 37 37 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 19 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 64 37 10 0 0 0 0 0 0 0 0 0 28 % N
% Pro: 0 0 0 0 0 0 10 0 0 0 0 0 46 82 19 % P
% Gln: 0 10 0 28 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 10 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 10 10 10 10 46 28 0 10 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % T
% Val: 55 10 0 0 28 28 0 0 0 0 46 19 0 0 10 % V
% Trp: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 37 37 10 19 0 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _