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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POU3F4 All Species: 14.24
Human Site: S127 Identified Species: 24.1
UniProt: P49335 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49335 NP_000298.2 361 39427 S127 P N P S I T S S G Q P L N V Y
Chimpanzee Pan troglodytes Q7YR49 360 38582 A121 P C T V T P G A V K L E K E K
Rhesus Macaque Macaca mulatta Q5TM49 360 38511 A121 P C T V P T G A V K L E K E K
Dog Lupus familis XP_549108 361 39472 S127 P N P S I T S S G Q P L N V Y
Cat Felis silvestris
Mouse Mus musculus P31360 445 47130 A185 H L P P S M G A S N G G L L Y
Rat Rattus norvegicus P62516 361 39399 S127 P N S S I T S S G Q P L N V Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518292 306 33617 T92 K D S W A V E T L G E R K T V
Chicken Gallus gallus P15143 739 75964 I169 P L S Q P I Q I A Q H L Q Q L
Frog Xenopus laevis P70030 385 41967 S134 H L S S M A S S N G Q G L L Y
Zebra Danio Brachydanio rerio P79746 378 41798 S134 H I P S M A T S N G Q S L I Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16241 427 45909 G144 A W H A P H A G H Y A P T G G
Honey Bee Apis mellifera XP_393686 460 49306 G183 A H Y N P S G G A A S P T T L
Nematode Worm Caenorhab. elegans P20268 380 42556 S129 S S I I N Q T S V V T S T P S
Sea Urchin Strong. purpuratus XP_782909 467 49786 M145 W N T G N A H M A M P M S M T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.3 39.3 96.6 N.A. 53.9 98.6 N.A. 49 22.6 60.7 60.8 N.A. 45.9 45.6 41 43.9
Protein Similarity: 100 50.4 49.8 98.6 N.A. 60.9 98.8 N.A. 55.6 30.5 69.8 72.4 N.A. 53.6 53.7 52.3 53.5
P-Site Identity: 100 6.6 13.3 100 N.A. 13.3 93.3 N.A. 0 20 26.6 26.6 N.A. 0 0 6.6 13.3
P-Site Similarity: 100 20 26.6 100 N.A. 26.6 93.3 N.A. 13.3 20 40 46.6 N.A. 13.3 20 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 8 8 22 8 22 22 8 8 0 0 0 0 % A
% Cys: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 0 0 8 15 0 15 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 29 15 22 22 8 15 0 8 8 % G
% His: 22 8 8 0 0 8 8 0 8 0 8 0 0 0 0 % H
% Ile: 0 8 8 8 22 8 0 8 0 0 0 0 0 8 0 % I
% Lys: 8 0 0 0 0 0 0 0 0 15 0 0 22 0 15 % K
% Leu: 0 22 0 0 0 0 0 0 8 0 15 29 22 15 15 % L
% Met: 0 0 0 0 15 8 0 8 0 8 0 8 0 8 0 % M
% Asn: 0 29 0 8 15 0 0 0 15 8 0 0 22 0 0 % N
% Pro: 43 0 29 8 29 8 0 0 0 0 29 15 0 8 0 % P
% Gln: 0 0 0 8 0 8 8 0 0 29 15 0 8 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 8 8 29 36 8 8 29 43 8 0 8 15 8 0 8 % S
% Thr: 0 0 22 0 8 29 15 8 0 0 8 0 22 15 8 % T
% Val: 0 0 0 15 0 8 0 0 22 8 0 0 0 22 8 % V
% Trp: 8 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 43 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _