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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POU3F4 All Species: 15.76
Human Site: S14 Identified Species: 26.67
UniProt: P49335 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49335 NP_000298.2 361 39427 S14 N P Y S I L S S T S L V H A D
Chimpanzee Pan troglodytes Q7YR49 360 38582 P14 S D F A F S P P P G G G G D G
Rhesus Macaque Macaca mulatta Q5TM49 360 38511 P14 S D F A F S P P P G G G G D G
Dog Lupus familis XP_549108 361 39472 S14 N P Y S I L S S S S L V H A D
Cat Felis silvestris
Mouse Mus musculus P31360 445 47130 A16 Y S L L T S S A S I V H A E P
Rat Rattus norvegicus P62516 361 39399 S14 N P Y S I L S S S S L V H A D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518292 306 33617
Chicken Gallus gallus P15143 739 75964 A64 A G T S L Q A A A Q S L N V Q
Frog Xenopus laevis P70030 385 41967 G15 H Y N L L G S G S S I V H A D
Zebra Danio Brachydanio rerio P79746 378 41798 S15 H Y N I L T S S P S I V H S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16241 427 45909 S26 G G G G Y H T S S P R S A A D
Honey Bee Apis mellifera XP_393686 460 49306 G22 S E L D G G S G T A I G M N I
Nematode Worm Caenorhab. elegans P20268 380 42556 A15 S I P S S L S A S A S D S E P
Sea Urchin Strong. purpuratus XP_782909 467 49786 S14 T P Y S L S L S Q A D I T P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.3 39.3 96.6 N.A. 53.9 98.6 N.A. 49 22.6 60.7 60.8 N.A. 45.9 45.6 41 43.9
Protein Similarity: 100 50.4 49.8 98.6 N.A. 60.9 98.8 N.A. 55.6 30.5 69.8 72.4 N.A. 53.6 53.7 52.3 53.5
P-Site Identity: 100 0 0 93.3 N.A. 6.6 93.3 N.A. 0 6.6 40 33.3 N.A. 20 13.3 20 26.6
P-Site Similarity: 100 20 20 100 N.A. 26.6 100 N.A. 0 40 66.6 66.6 N.A. 33.3 33.3 46.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 15 0 0 8 22 8 22 0 0 15 36 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 8 0 0 0 0 0 0 8 8 0 15 36 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 0 0 15 8 % E
% Phe: 0 0 15 0 15 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 15 8 8 8 15 0 15 0 15 15 22 15 0 15 % G
% His: 15 0 0 0 0 8 0 0 0 0 0 8 36 0 0 % H
% Ile: 0 8 0 8 22 0 0 0 0 8 22 8 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 15 15 29 29 8 0 0 0 22 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 22 0 15 0 0 0 0 0 0 0 0 0 8 8 0 % N
% Pro: 0 29 8 0 0 0 15 15 22 8 0 0 0 8 15 % P
% Gln: 0 0 0 0 0 8 0 0 8 8 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 29 8 0 43 8 29 58 43 43 36 15 8 8 8 8 % S
% Thr: 8 0 8 0 8 8 8 0 15 0 0 0 8 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 8 36 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 15 29 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _