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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POU3F4 All Species: 14.85
Human Site: S161 Identified Species: 25.13
UniProt: P49335 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49335 NP_000298.2 361 39427 S161 P A A A S A Q S L H P V L R E
Chimpanzee Pan troglodytes Q7YR49 360 38582 Q155 Q F A K L L K Q K R I T L G Y
Rhesus Macaque Macaca mulatta Q5TM49 360 38511 Q155 Q F A K L L K Q K R I T L G Y
Dog Lupus familis XP_549108 361 39472 S161 P G S A S A Q S L H P V L R D
Cat Felis silvestris
Mouse Mus musculus P31360 445 47130 D219 L H H H G L R D A H D E P H H
Rat Rattus norvegicus P62516 361 39399 S161 P A A A S T Q S L H P V L R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518292 306 33617 P126 E N K R K G C P G G G G G G A
Chicken Gallus gallus P15143 739 75964 S203 Q P A Q F I I S Q T P Q G Q Q
Frog Xenopus laevis P70030 385 41967 S168 H H H G L R D S H D D H H G D
Zebra Danio Brachydanio rerio P79746 378 41798 H168 H H S M R D A H E D H H S P H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16241 427 45909 S178 V A A A H H Q S V A P L H H T
Honey Bee Apis mellifera XP_393686 460 49306 T217 P Q L H N H Q T G L H P N L R
Nematode Worm Caenorhab. elegans P20268 380 42556 S163 W P P A Y Q F S C D D S G S V
Sea Urchin Strong. purpuratus XP_782909 467 49786 A179 H P M Y T Y G A M N G M M S C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.3 39.3 96.6 N.A. 53.9 98.6 N.A. 49 22.6 60.7 60.8 N.A. 45.9 45.6 41 43.9
Protein Similarity: 100 50.4 49.8 98.6 N.A. 60.9 98.8 N.A. 55.6 30.5 69.8 72.4 N.A. 53.6 53.7 52.3 53.5
P-Site Identity: 100 13.3 13.3 80 N.A. 6.6 93.3 N.A. 0 20 6.6 0 N.A. 40 13.3 13.3 0
P-Site Similarity: 100 20 20 93.3 N.A. 13.3 93.3 N.A. 0 33.3 13.3 6.6 N.A. 53.3 26.6 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 43 36 0 15 8 8 8 8 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 8 8 8 0 22 22 0 0 0 15 % D
% Glu: 8 0 0 0 0 0 0 0 8 0 0 8 0 0 15 % E
% Phe: 0 15 0 0 8 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 8 8 8 8 0 15 8 15 8 22 29 0 % G
% His: 22 22 15 15 8 15 0 8 8 29 15 15 15 15 15 % H
% Ile: 0 0 0 0 0 8 8 0 0 0 15 0 0 0 0 % I
% Lys: 0 0 8 15 8 0 15 0 15 0 0 0 0 0 0 % K
% Leu: 8 0 8 0 22 22 0 0 22 8 0 8 36 8 0 % L
% Met: 0 0 8 8 0 0 0 0 8 0 0 8 8 0 0 % M
% Asn: 0 8 0 0 8 0 0 0 0 8 0 0 8 0 0 % N
% Pro: 29 22 8 0 0 0 0 8 0 0 36 8 8 8 0 % P
% Gln: 22 8 0 8 0 8 36 15 8 0 0 8 0 8 8 % Q
% Arg: 0 0 0 8 8 8 8 0 0 15 0 0 0 22 8 % R
% Ser: 0 0 15 0 22 0 0 50 0 0 0 8 8 15 0 % S
% Thr: 0 0 0 0 8 8 0 8 0 8 0 15 0 0 8 % T
% Val: 8 0 0 0 0 0 0 0 8 0 0 22 0 0 8 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 8 8 0 0 0 0 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _