KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POU3F4
All Species:
36.36
Human Site:
S268
Identified Species:
61.54
UniProt:
P49335
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49335
NP_000298.2
361
39427
S268
S
S
T
G
S
P
T
S
I
D
K
I
A
A
Q
Chimpanzee
Pan troglodytes
Q7YR49
360
38582
H262
P
T
L
Q
Q
I
S
H
I
A
Q
Q
L
G
L
Rhesus Macaque
Macaca mulatta
Q5TM49
360
38511
H262
P
T
L
Q
Q
I
S
H
I
A
Q
Q
L
G
L
Dog
Lupus familis
XP_549108
361
39472
S268
S
S
T
G
S
P
T
S
I
D
K
I
A
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
P31360
445
47130
S346
S
S
S
G
S
P
T
S
I
D
K
I
A
A
Q
Rat
Rattus norvegicus
P62516
361
39399
S268
S
S
T
G
S
P
T
S
I
D
K
I
A
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518292
306
33617
K222
K
L
K
P
L
L
N
K
W
L
E
E
A
D
S
Chicken
Gallus gallus
P15143
739
75964
P365
S
P
S
A
L
N
S
P
G
Q
G
I
E
G
V
Frog
Xenopus laevis
P70030
385
41967
S286
S
S
S
G
S
P
T
S
I
D
K
I
A
A
Q
Zebra Danio
Brachydanio rerio
P79746
378
41798
S282
S
T
S
G
S
P
T
S
L
D
K
I
A
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16241
427
45909
S294
S
T
T
G
S
P
T
S
I
D
K
I
A
A
Q
Honey Bee
Apis mellifera
XP_393686
460
49306
S331
S
T
T
G
S
P
T
S
I
D
K
I
A
A
Q
Nematode Worm
Caenorhab. elegans
P20268
380
42556
F271
T
G
S
P
N
S
T
F
E
K
M
T
G
Q
A
Sea Urchin
Strong. purpuratus
XP_782909
467
49786
S301
S
T
S
G
S
P
T
S
L
D
K
I
A
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.3
39.3
96.6
N.A.
53.9
98.6
N.A.
49
22.6
60.7
60.8
N.A.
45.9
45.6
41
43.9
Protein Similarity:
100
50.4
49.8
98.6
N.A.
60.9
98.8
N.A.
55.6
30.5
69.8
72.4
N.A.
53.6
53.7
52.3
53.5
P-Site Identity:
100
6.6
6.6
100
N.A.
93.3
100
N.A.
6.6
13.3
93.3
80
N.A.
93.3
93.3
6.6
80
P-Site Similarity:
100
26.6
26.6
100
N.A.
100
100
N.A.
13.3
26.6
100
100
N.A.
100
100
26.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
15
0
0
72
65
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
65
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
8
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
65
0
0
0
0
8
0
8
0
8
22
0
% G
% His:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
15
0
0
65
0
0
72
0
0
0
% I
% Lys:
8
0
8
0
0
0
0
8
0
8
65
0
0
0
0
% K
% Leu:
0
8
15
0
15
8
0
0
15
8
0
0
15
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
8
8
8
0
0
0
0
0
0
0
0
% N
% Pro:
15
8
0
15
0
65
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
15
15
0
0
0
0
8
15
15
0
8
65
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
72
36
43
0
65
8
22
65
0
0
0
0
0
0
8
% S
% Thr:
8
43
36
0
0
0
72
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _