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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FNTA All Species: 32.73
Human Site: S290 Identified Species: 55.38
UniProt: P49354 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49354 NP_001018196.1 379 44409 S290 I L Q D R G L S K Y P N L L N
Chimpanzee Pan troglodytes XP_001145861 341 40476 S252 I L Q D R G L S K Y P N L L N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532786 380 44552 S291 I L Q D R G L S R Y P N L L S
Cat Felis silvestris
Mouse Mus musculus Q61239 377 43995 S290 I L Q D R G L S R Y P N L L N
Rat Rattus norvegicus Q04631 377 44031 S290 I L Q D R G L S R Y P N L L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509604 295 34797 L223 L E Y V D H L L K E D V R N N
Chicken Gallus gallus XP_424881 452 52486 S361 I L Q D R G L S K Y P N L L E
Frog Xenopus laevis NP_001108255 379 44692 S283 I L Q E R G M S E Y P N L L E
Zebra Danio Brachydanio rerio NP_001074029 374 43333 S268 I L Q D G G L S S Y P G L L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608862 331 38889 A243 R Q G D S G N A L L S S Y P D
Honey Bee Apis mellifera XP_624123 328 39039 G240 I L M H D S N G L A Y N E K V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784125 218 26020 T146 P S N E L N F T E S I L E K D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LX33 340 39441 S250 L Y K D D K E S W I S D P S V
Baker's Yeast Sacchar. cerevisiae P29703 316 37489 V241 R L Q W D S K V V D F A T T F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.7 N.A. 94.7 N.A. 92 92.3 N.A. 60.4 68.3 70.9 60.4 N.A. 43.2 44.3 N.A. 39.5
Protein Similarity: 100 89.7 N.A. 97.1 N.A. 96 96 N.A. 65.4 75.2 81.5 78.6 N.A. 63.8 61.7 N.A. 49
P-Site Identity: 100 100 N.A. 86.6 N.A. 93.3 93.3 N.A. 20 93.3 73.3 73.3 N.A. 13.3 20 N.A. 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 26.6 93.3 93.3 73.3 N.A. 33.3 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 35.6 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. 53.3 40.1 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 8 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 65 29 0 0 0 0 8 8 8 0 0 15 % D
% Glu: 0 8 0 15 0 0 8 0 15 8 0 0 15 0 22 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 8 % F
% Gly: 0 0 8 0 8 65 0 8 0 0 0 8 0 0 0 % G
% His: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 65 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % I
% Lys: 0 0 8 0 0 8 8 0 29 0 0 0 0 15 0 % K
% Leu: 15 72 0 0 8 0 58 8 15 8 0 8 58 58 0 % L
% Met: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 8 15 0 0 0 0 58 0 8 36 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 58 0 8 8 0 % P
% Gln: 0 8 65 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 15 0 0 0 50 0 0 0 22 0 0 0 8 0 0 % R
% Ser: 0 8 0 0 8 15 0 65 8 8 15 8 0 8 8 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 0 8 8 0 % T
% Val: 0 0 0 8 0 0 0 8 8 0 0 8 0 0 15 % V
% Trp: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 0 0 0 0 0 58 8 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _