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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FNTB All Species: 20.91
Human Site: S183 Identified Species: 32.86
UniProt: P49356 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49356 NP_002019.1 437 48774 S183 K L L Q Y L Y S L K Q P D G S
Chimpanzee Pan troglodytes XP_510007 413 46090 A184 V R S A Y C A A S V A S L T N
Rhesus Macaque Macaca mulatta XP_001103300 437 48755 S183 K L L Q Y L Y S L K Q P D G S
Dog Lupus familis XP_547857 437 48734 S183 K L L Q Y L Y S L K Q P D G S
Cat Felis silvestris
Mouse Mus musculus Q8K2I1 437 48801 S183 K L L Q Y L Y S L K Q P D G S
Rat Rattus norvegicus Q02293 437 48655 S183 K L L Q Y L Y S L K Q P D G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514848 482 53625 A188 G L R Q L T D A Y E C L D A S
Chicken Gallus gallus
Frog Xenopus laevis NP_001087781 414 45832 H179 A D G S F T M H I G G E V D V
Zebra Danio Brachydanio rerio NP_001002128 419 46406 H179 P D G S F V M H I G G E V D V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650540 419 46693 V182 D G S F R L H V D G E T D V R
Honey Bee Apis mellifera XP_625117 401 45218 K179 D G S F S L H K D G E T D I R
Nematode Worm Caenorhab. elegans P41992 335 37207 S116 Q T L I I F N S I E K A D A D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001140519 452 49588 R180 K D V S G A F R M H D G G E I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38920 404 45179 T182 S E A H G G Y T Y C G L A A M
Baker's Yeast Sacchar. cerevisiae P22007 431 48171 L192 I Y Q W L I S L K E P N G G F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.8 99.5 96.5 N.A. 95.8 96.5 N.A. 42.9 N.A. 70.2 67.5 N.A. 45.7 48.7 23.1 N.A.
Protein Similarity: 100 91.3 100 98.4 N.A. 98.8 98.8 N.A. 54.7 N.A. 80.7 78.4 N.A. 60.6 64 42.5 N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 26.6 N.A. 0 0 N.A. 13.3 13.3 20 N.A.
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 40 N.A. 13.3 20 N.A. 26.6 26.6 46.6 N.A.
Percent
Protein Identity: N.A. 37.6 N.A. 21.7 36.1 N.A.
Protein Similarity: N.A. 51.7 N.A. 34.3 51.7 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. 26.6 N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 7 0 7 7 14 0 0 7 7 7 20 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 7 7 0 0 0 0 % C
% Asp: 14 20 0 0 0 0 7 0 14 0 7 0 60 14 7 % D
% Glu: 0 7 0 0 0 0 0 0 0 20 14 14 0 7 0 % E
% Phe: 0 0 0 14 14 7 7 0 0 0 0 0 0 0 7 % F
% Gly: 7 14 14 0 14 7 0 0 0 27 20 7 14 40 0 % G
% His: 0 0 0 7 0 0 14 14 0 7 0 0 0 0 0 % H
% Ile: 7 0 0 7 7 7 0 0 20 0 0 0 0 7 7 % I
% Lys: 40 0 0 0 0 0 0 7 7 34 7 0 0 0 0 % K
% Leu: 0 40 40 0 14 47 0 7 34 0 0 14 7 0 0 % L
% Met: 0 0 0 0 0 0 14 0 7 0 0 0 0 0 7 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 7 % N
% Pro: 7 0 0 0 0 0 0 0 0 0 7 34 0 0 0 % P
% Gln: 7 0 7 40 0 0 0 0 0 0 34 0 0 0 0 % Q
% Arg: 0 7 7 0 7 0 0 7 0 0 0 0 0 0 14 % R
% Ser: 7 0 20 20 7 0 7 40 7 0 0 7 0 0 40 % S
% Thr: 0 7 0 0 0 14 0 7 0 0 0 14 0 7 0 % T
% Val: 7 0 7 0 0 7 0 7 0 7 0 0 14 7 14 % V
% Trp: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 40 0 40 0 14 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _