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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FNTB All Species: 20.61
Human Site: Y180 Identified Species: 32.38
UniProt: P49356 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49356 NP_002019.1 437 48774 Y180 N R E K L L Q Y L Y S L K Q P
Chimpanzee Pan troglodytes XP_510007 413 46090 Y181 E V D V R S A Y C A A S V A S
Rhesus Macaque Macaca mulatta XP_001103300 437 48755 Y180 N R E K L L Q Y L Y S L K Q P
Dog Lupus familis XP_547857 437 48734 Y180 N R E K L L Q Y L Y S L K Q P
Cat Felis silvestris
Mouse Mus musculus Q8K2I1 437 48801 Y180 N R E K L L Q Y L Y S L K Q P
Rat Rattus norvegicus Q02293 437 48655 Y180 N R E K L L Q Y L Y S L K Q P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514848 482 53625 L185 L K R G L R Q L T D A Y E C L
Chicken Gallus gallus
Frog Xenopus laevis NP_001087781 414 45832 F176 L K Q A D G S F T M H I G G E
Zebra Danio Brachydanio rerio NP_001002128 419 46406 F176 V K Q P D G S F V M H I G G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650540 419 46693 R179 R D S D G S F R L H V D G E T
Honey Bee Apis mellifera XP_625117 401 45218 S176 H G E D G S F S L H K D G E T
Nematode Worm Caenorhab. elegans P41992 335 37207 I113 C A V Q T L I I F N S I E K A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001140519 452 49588 G177 L Q M K D V S G A F R M H D G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38920 404 45179 G179 E P G S E A H G G Y T Y C G L
Baker's Yeast Sacchar. cerevisiae P22007 431 48171 L189 R K G I Y Q W L I S L K E P N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.8 99.5 96.5 N.A. 95.8 96.5 N.A. 42.9 N.A. 70.2 67.5 N.A. 45.7 48.7 23.1 N.A.
Protein Similarity: 100 91.3 100 98.4 N.A. 98.8 98.8 N.A. 54.7 N.A. 80.7 78.4 N.A. 60.6 64 42.5 N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 13.3 N.A. 0 0 N.A. 6.6 13.3 13.3 N.A.
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 33.3 N.A. 26.6 33.3 N.A. 20 33.3 40 N.A.
Percent
Protein Identity: N.A. 37.6 N.A. 21.7 36.1 N.A.
Protein Similarity: N.A. 51.7 N.A. 34.3 51.7 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 0 N.A.
P-Site Similarity: N.A. 33.3 N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 0 7 7 0 7 7 14 0 0 7 7 % A
% Cys: 7 0 0 0 0 0 0 0 7 0 0 0 7 7 0 % C
% Asp: 0 7 7 14 20 0 0 0 0 7 0 14 0 7 0 % D
% Glu: 14 0 40 0 7 0 0 0 0 0 0 0 20 14 14 % E
% Phe: 0 0 0 0 0 0 14 14 7 7 0 0 0 0 0 % F
% Gly: 0 7 14 7 14 14 0 14 7 0 0 0 27 20 7 % G
% His: 7 0 0 0 0 0 7 0 0 14 14 0 7 0 0 % H
% Ile: 0 0 0 7 0 0 7 7 7 0 0 20 0 0 0 % I
% Lys: 0 27 0 40 0 0 0 0 0 0 7 7 34 7 0 % K
% Leu: 20 0 0 0 40 40 0 14 47 0 7 34 0 0 14 % L
% Met: 0 0 7 0 0 0 0 0 0 14 0 7 0 0 0 % M
% Asn: 34 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % N
% Pro: 0 7 0 7 0 0 0 0 0 0 0 0 0 7 34 % P
% Gln: 0 7 14 7 0 7 40 0 0 0 0 0 0 34 0 % Q
% Arg: 14 34 7 0 7 7 0 7 0 0 7 0 0 0 0 % R
% Ser: 0 0 7 7 0 20 20 7 0 7 40 7 0 0 7 % S
% Thr: 0 0 0 0 7 0 0 0 14 0 7 0 0 0 14 % T
% Val: 7 7 7 7 0 7 0 0 7 0 7 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 40 0 40 0 14 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _