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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHPS
All Species:
52.42
Human Site:
S204
Identified Species:
88.72
UniProt:
P49366
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49366
NP_001921.1
369
40971
S204
E
G
V
K
W
T
P
S
K
M
I
A
R
L
G
Chimpanzee
Pan troglodytes
XP_001169027
369
40978
S204
E
G
V
K
W
T
P
S
K
M
I
A
R
L
G
Rhesus Macaque
Macaca mulatta
XP_001108116
369
40824
S204
E
G
V
K
W
T
P
S
K
M
I
A
R
L
G
Dog
Lupus familis
XP_533907
369
40772
S204
E
G
V
K
W
T
P
S
K
M
I
A
R
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3TXU5
369
40564
S204
E
G
V
K
W
T
P
S
K
M
I
S
R
L
G
Rat
Rattus norvegicus
Q6AY53
369
40687
S204
E
G
V
K
W
T
P
S
K
M
I
S
R
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084929
349
38490
S183
E
G
T
K
W
T
P
S
K
M
I
A
R
L
G
Zebra Danio
Brachydanio rerio
NP_998387
361
39982
S196
E
G
T
H
W
T
P
S
K
M
I
H
R
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSF4
368
41061
S199
Q
G
T
I
W
S
P
S
K
I
I
H
R
L
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XXJ0
371
40449
S211
K
H
L
N
W
T
P
S
K
L
I
Q
R
L
G
Sea Urchin
Strong. purpuratus
XP_001201794
380
42272
S200
E
G
I
N
W
T
P
S
K
M
I
A
R
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FI94
368
41045
S203
E
N
V
L
W
T
P
S
K
L
L
A
R
L
G
Baker's Yeast
Sacchar. cerevisiae
P38791
387
42874
S223
D
S
P
I
W
T
P
S
K
M
I
D
R
F
G
Red Bread Mold
Neurospora crassa
P49365
353
38924
S194
N
E
I
N
W
T
P
S
K
V
I
H
R
L
G
Conservation
Percent
Protein Identity:
100
99.1
97.5
94.5
N.A.
91
92.1
N.A.
N.A.
N.A.
72.9
75.6
N.A.
62.3
N.A.
58.7
63.1
Protein Similarity:
100
99.4
98.9
96.7
N.A.
94.8
94.5
N.A.
N.A.
N.A.
83.7
86.9
N.A.
78.3
N.A.
76
79.2
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
93.3
80
N.A.
60
N.A.
60
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
93.3
80
N.A.
80
N.A.
80
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
61.5
55.3
56.3
Protein Similarity:
N.A.
N.A.
N.A.
76.6
71.8
69.1
P-Site Identity:
N.A.
N.A.
N.A.
73.3
60
60
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
66.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
72
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
100
% G
% His:
0
8
0
8
0
0
0
0
0
0
0
22
0
0
0
% H
% Ile:
0
0
15
15
0
0
0
0
0
8
93
0
0
0
0
% I
% Lys:
8
0
0
50
0
0
0
0
100
0
0
0
0
0
0
% K
% Leu:
0
0
8
8
0
0
0
0
0
15
8
0
0
93
0
% L
% Met:
0
0
0
0
0
0
0
0
0
72
0
0
0
0
0
% M
% Asn:
8
8
0
22
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
100
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% R
% Ser:
0
8
0
0
0
8
0
100
0
0
0
15
0
0
0
% S
% Thr:
0
0
22
0
0
93
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
50
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _