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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHPS
All Species:
23.94
Human Site:
S28
Identified Species:
40.51
UniProt:
P49366
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49366
NP_001921.1
369
40971
S28
S
S
T
L
P
P
E
S
T
Q
V
R
G
Y
D
Chimpanzee
Pan troglodytes
XP_001169027
369
40978
S28
S
S
T
L
P
P
E
S
T
Q
V
R
G
Y
D
Rhesus Macaque
Macaca mulatta
XP_001108116
369
40824
S28
S
S
T
L
P
P
E
S
T
Q
V
R
G
Y
D
Dog
Lupus familis
XP_533907
369
40772
S28
S
S
A
L
P
S
E
S
S
Q
V
R
G
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3TXU5
369
40564
S28
S
S
A
L
P
P
E
S
A
Q
V
Q
G
Y
D
Rat
Rattus norvegicus
Q6AY53
369
40687
S28
S
S
A
L
P
P
E
S
A
Q
V
Q
G
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084929
349
38490
Q26
S
L
P
E
G
S
V
Q
V
R
G
Y
D
F
N
Zebra Danio
Brachydanio rerio
NP_998387
361
39982
Q26
P
L
P
D
N
L
P
Q
I
R
G
Y
D
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSF4
368
41061
Y29
N
T
P
Q
V
S
G
Y
D
F
N
E
G
L
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XXJ0
371
40449
R35
P
D
G
S
I
P
I
R
G
F
D
F
S
T
A
Sea Urchin
Strong. purpuratus
XP_001201794
380
42272
Y29
D
S
V
K
V
K
G
Y
D
F
N
E
G
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FI94
368
41045
Y31
K
C
D
K
I
E
G
Y
D
F
N
Q
G
V
D
Baker's Yeast
Sacchar. cerevisiae
P38791
387
42874
Q31
P
D
D
F
V
K
V
Q
G
I
D
Y
S
K
P
Red Bread Mold
Neurospora crassa
P49365
353
38924
K27
E
M
P
E
G
S
Q
K
V
E
E
L
D
F
N
Conservation
Percent
Protein Identity:
100
99.1
97.5
94.5
N.A.
91
92.1
N.A.
N.A.
N.A.
72.9
75.6
N.A.
62.3
N.A.
58.7
63.1
Protein Similarity:
100
99.4
98.9
96.7
N.A.
94.8
94.5
N.A.
N.A.
N.A.
83.7
86.9
N.A.
78.3
N.A.
76
79.2
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
N.A.
N.A.
6.6
0
N.A.
13.3
N.A.
6.6
20
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
N.A.
26.6
20
N.A.
26.6
N.A.
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
61.5
55.3
56.3
Protein Similarity:
N.A.
N.A.
N.A.
76.6
71.8
69.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
0
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
22
0
0
0
0
0
15
0
0
0
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
15
8
0
0
0
0
22
0
15
0
22
0
65
% D
% Glu:
8
0
0
15
0
8
43
0
0
8
8
15
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
29
0
8
0
22
0
% F
% Gly:
0
0
8
0
15
0
22
0
15
0
15
0
65
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
0
8
0
8
8
0
0
0
8
0
% I
% Lys:
8
0
0
15
0
15
0
8
0
0
0
0
0
8
0
% K
% Leu:
0
15
0
43
0
8
0
0
0
0
0
8
0
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
0
0
22
0
0
0
22
% N
% Pro:
22
0
29
0
43
43
8
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
8
0
0
8
22
0
43
0
22
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
15
0
29
0
0
0
% R
% Ser:
50
50
0
8
0
29
0
43
8
0
0
0
15
0
0
% S
% Thr:
0
8
22
0
0
0
0
0
22
0
0
0
0
8
0
% T
% Val:
0
0
8
0
22
0
15
0
15
0
43
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
22
0
0
0
22
0
43
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _