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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARRB1
All Species:
25.97
Human Site:
S412
Identified Species:
51.95
UniProt:
P49407
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49407
NP_004032.2
418
47066
S412
E
E
E
D
G
T
G
S
P
Q
L
N
N
R
_
Chimpanzee
Pan troglodytes
XP_508643
418
46958
S412
E
E
E
D
G
T
G
S
P
Q
L
N
N
R
_
Rhesus Macaque
Macaca mulatta
XP_001083881
431
47846
S425
E
E
E
N
G
T
G
S
P
Q
L
N
N
R
_
Dog
Lupus familis
XP_850043
413
46428
S407
E
E
E
D
G
T
G
S
P
Q
L
N
D
R
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWG8
418
46954
S412
E
E
D
D
G
T
G
S
P
H
L
N
N
R
_
Rat
Rattus norvegicus
P29066
418
47001
S412
E
E
D
D
G
T
G
S
P
H
L
N
N
R
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001091002
395
44143
Frog
Xenopus laevis
P51483
387
43027
E381
K
L
Q
G
A
E
G
E
D
D
K
D
D
A
_
Zebra Danio
Brachydanio rerio
NP_001153294
418
46918
S412
E
D
E
E
G
A
D
S
P
K
L
N
D
R
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P19107
401
45010
Honey Bee
Apis mellifera
XP_392535
414
45893
Nematode Worm
Caenorhab. elegans
P51485
435
48440
N429
D
Q
P
S
P
S
A
N
L
P
P
S
L
L
_
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
83
98
N.A.
98.5
99
N.A.
N.A.
66.7
57.4
90.6
N.A.
39.7
58.1
51.9
N.A.
Protein Similarity:
100
99
86.5
98.5
N.A.
99.2
99.7
N.A.
N.A.
80.6
75.8
96.6
N.A.
60.5
72.7
65.2
N.A.
P-Site Identity:
100
100
92.8
92.8
N.A.
85.7
85.7
N.A.
N.A.
0
7.1
57.1
N.A.
0
0
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
92.8
92.8
N.A.
N.A.
0
35.7
85.7
N.A.
0
0
35.7
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
9
9
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
17
42
0
0
9
0
9
9
0
9
25
0
0
% D
% Glu:
59
50
42
9
0
9
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
59
0
59
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% K
% Leu:
0
9
0
0
0
0
0
0
9
0
59
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
9
0
0
0
59
42
0
0
% N
% Pro:
0
0
9
0
9
0
0
0
59
9
9
0
0
0
0
% P
% Gln:
0
9
9
0
0
0
0
0
0
34
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
59
0
% R
% Ser:
0
0
0
9
0
9
0
59
0
0
0
9
0
0
0
% S
% Thr:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% _