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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARRB1
All Species:
33.03
Human Site:
Y173
Identified Species:
66.06
UniProt:
P49407
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49407
NP_004032.2
418
47066
Y173
L
V
I
R
K
V
Q
Y
A
P
E
R
P
G
P
Chimpanzee
Pan troglodytes
XP_508643
418
46958
Y173
L
V
I
R
K
V
Q
Y
A
P
E
R
P
G
P
Rhesus Macaque
Macaca mulatta
XP_001083881
431
47846
Y191
L
V
I
R
K
V
Q
Y
A
P
E
R
P
G
P
Dog
Lupus familis
XP_850043
413
46428
Y168
L
V
I
R
K
V
Q
Y
A
P
E
R
P
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWG8
418
46954
Y173
L
V
I
R
K
V
Q
Y
A
P
E
R
P
G
P
Rat
Rattus norvegicus
P29066
418
47001
Y173
L
V
I
R
K
V
Q
Y
A
P
E
R
P
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001091002
395
44143
F173
L
V
I
R
K
I
Q
F
A
P
M
K
T
G
P
Frog
Xenopus laevis
P51483
387
43027
R168
N
S
V
Q
L
I
I
R
K
V
Q
F
A
P
E
Zebra Danio
Brachydanio rerio
NP_001153294
418
46918
Y173
L
V
I
R
K
V
Q
Y
A
P
E
K
P
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P19107
401
45010
A172
V
I
K
K
L
Q
Y
A
P
L
N
R
G
Q
R
Honey Bee
Apis mellifera
XP_392535
414
45893
Y181
L
A
I
R
K
I
M
Y
A
P
S
K
Q
G
E
Nematode Worm
Caenorhab. elegans
P51485
435
48440
Y185
L
A
I
R
K
L
T
Y
A
P
F
E
S
R
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
83
98
N.A.
98.5
99
N.A.
N.A.
66.7
57.4
90.6
N.A.
39.7
58.1
51.9
N.A.
Protein Similarity:
100
99
86.5
98.5
N.A.
99.2
99.7
N.A.
N.A.
80.6
75.8
96.6
N.A.
60.5
72.7
65.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
66.6
0
93.3
N.A.
6.6
53.3
53.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
26.6
100
N.A.
26.6
66.6
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
0
0
0
9
84
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
59
9
0
0
17
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
9
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
9
75
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
84
0
0
25
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
9
84
0
0
0
9
0
0
25
0
0
0
% K
% Leu:
84
0
0
0
17
9
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
84
0
0
59
9
75
% P
% Gln:
0
0
0
9
0
9
67
0
0
0
9
0
9
9
0
% Q
% Arg:
0
0
0
84
0
0
0
9
0
0
0
59
0
9
9
% R
% Ser:
0
9
0
0
0
0
0
0
0
0
9
0
9
0
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% T
% Val:
9
67
9
0
0
59
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _