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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUFM All Species: 41.52
Human Site: S345 Identified Species: 83.03
UniProt: P49411 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49411 NP_003312.3 452 49542 S345 L V M V K P G S I K P H Q K V
Chimpanzee Pan troglodytes XP_001142719 446 49012 S339 L V M V K P G S I K P H Q K V
Rhesus Macaque Macaca mulatta XP_001103519 455 49928 S348 L V M V K P G S I K P H Q K V
Dog Lupus familis XP_536924 583 63111 S476 L V M A K P G S I Q P H Q K V
Cat Felis silvestris
Mouse Mus musculus Q8BFR5 452 49490 S345 L V M V K P G S I Q P H Q K V
Rat Rattus norvegicus P85834 452 49504 S345 L V M V K P G S I Q P H Q K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519351 429 47011 S322 L V M A K P G S I Q P H Q K V
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001013523 448 49226 S340 M V M I K P G S I Q P H Q K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524752 489 53974 S369 M V M C K P G S V K A L D Q L
Honey Bee Apis mellifera XP_623051 469 52402 T349 M V L C K P G T M K A N D H L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788937 452 50023 V350 M V M C K P G V L S P H N N F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P02992 437 47954 T337 M V L A K P G T V K A H T K I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 97.1 72.3 N.A. 93.5 93.8 N.A. 83.1 N.A. N.A. 71.9 N.A. 59.5 56.2 N.A. 61.7
Protein Similarity: 100 98 98.2 74.4 N.A. 96.2 96.2 N.A. 89.3 N.A. N.A. 84.9 N.A. 74.4 71.6 N.A. 78.7
P-Site Identity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 86.6 N.A. N.A. 73.3 N.A. 46.6 33.3 N.A. 46.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 93.3 N.A. N.A. 100 N.A. 73.3 73.3 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 56.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 71.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 25 0 0 0 0 0 0 25 0 0 0 0 % A
% Cys: 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 84 0 9 0 % H
% Ile: 0 0 0 9 0 0 0 0 67 0 0 0 0 0 17 % I
% Lys: 0 0 0 0 100 0 0 0 0 50 0 0 0 75 0 % K
% Leu: 59 0 17 0 0 0 0 0 9 0 0 9 0 0 17 % L
% Met: 42 0 84 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 9 9 0 % N
% Pro: 0 0 0 0 0 100 0 0 0 0 75 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 42 0 0 67 9 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 75 0 9 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 17 0 0 0 0 9 0 0 % T
% Val: 0 100 0 42 0 0 0 9 17 0 0 0 0 0 59 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _