KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUFM
All Species:
24.24
Human Site:
Y246
Identified Species:
48.48
UniProt:
P49411
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49411
NP_003312.3
452
49542
Y246
L
L
D
A
V
D
T
Y
I
P
V
P
A
R
D
Chimpanzee
Pan troglodytes
XP_001142719
446
49012
L248
I
P
V
P
A
R
D
L
E
K
P
F
L
L
P
Rhesus Macaque
Macaca mulatta
XP_001103519
455
49928
Y249
L
L
D
A
V
D
T
Y
I
P
V
P
T
R
D
Dog
Lupus familis
XP_536924
583
63111
Y377
L
L
D
A
V
D
T
Y
I
P
V
P
T
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFR5
452
49490
Y246
L
L
D
A
V
D
T
Y
I
P
V
P
T
R
D
Rat
Rattus norvegicus
P85834
452
49504
Y246
L
L
D
A
V
D
T
Y
I
P
V
P
T
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519351
429
47011
H223
L
L
D
A
V
D
T
H
I
P
V
P
T
R
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013523
448
49226
H241
L
L
E
V
I
D
G
H
I
P
L
P
S
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524752
489
53974
F270
L
L
Q
E
V
D
S
F
I
P
T
P
V
R
E
Honey Bee
Apis mellifera
XP_623051
469
52402
Y250
L
L
E
A
V
D
D
Y
I
P
T
P
I
R
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788937
452
50023
W251
L
M
E
A
V
D
S
W
I
P
L
P
L
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P02992
437
47954
Y237
L
L
D
A
V
D
E
Y
I
P
T
P
E
R
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
97.1
72.3
N.A.
93.5
93.8
N.A.
83.1
N.A.
N.A.
71.9
N.A.
59.5
56.2
N.A.
61.7
Protein Similarity:
100
98
98.2
74.4
N.A.
96.2
96.2
N.A.
89.3
N.A.
N.A.
84.9
N.A.
74.4
71.6
N.A.
78.7
P-Site Identity:
100
0
93.3
93.3
N.A.
93.3
93.3
N.A.
86.6
N.A.
N.A.
53.3
N.A.
53.3
73.3
N.A.
53.3
P-Site Similarity:
100
6.6
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
N.A.
86.6
N.A.
73.3
80
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
56.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
71.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
75
9
0
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
59
0
0
92
17
0
0
0
0
0
0
0
75
% D
% Glu:
0
0
25
9
0
0
9
0
9
0
0
0
9
0
17
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
0
0
0
92
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
92
84
0
0
0
0
0
9
0
0
17
0
17
9
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
9
0
0
0
0
0
92
9
92
0
0
9
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
0
0
92
0
% R
% Ser:
0
0
0
0
0
0
17
0
0
0
0
0
9
0
0
% S
% Thr:
0
0
0
0
0
0
50
0
0
0
25
0
42
0
0
% T
% Val:
0
0
9
9
84
0
0
0
0
0
50
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _