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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMPH All Species: 40.3
Human Site: T78 Identified Species: 98.52
UniProt: P49418 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49418 NP_001626.1 695 76257 T78 Q E A S M K L T E S L H E V Y
Chimpanzee Pan troglodytes XP_519055 930 101395 T181 Q E A S M K L T E S L H E V Y
Rhesus Macaque Macaca mulatta XP_001100126 694 76130 T78 Q E A S M K L T E S L H E V Y
Dog Lupus familis XP_533085 836 91248 T94 Q E A S M K L T E S L H E V Y
Cat Felis silvestris
Mouse Mus musculus Q7TQF7 686 74995 T78 Q E A S M K L T E S L H E V Y
Rat Rattus norvegicus O08838 683 74859 T78 Q E A S M K L T E S L H E V Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516791 687 75140 T78 Q E A S M K L T E S L H E V Y
Chicken Gallus gallus P50478 682 75187 T78 Q D A S K K L T E S L H E V Y
Frog Xenopus laevis NP_001085079 666 74474 S82 Q E A S L K L S E S L H E V Y
Zebra Danio Brachydanio rerio NP_957125 784 85747 T78 Q Q A S M N L T E S L H E V Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.7 97.4 63 N.A. 85.1 86.4 N.A. 74.9 72 61.4 50.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 73 98.2 68.6 N.A. 88 89 N.A. 82.3 80.5 71.6 64.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 86.6 86.6 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 100 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 80 0 0 0 0 0 0 100 0 0 0 100 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 90 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 100 0 0 0 100 0 0 0 0 % L
% Met: 0 0 0 0 80 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 100 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 100 0 0 0 10 0 100 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 90 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _