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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH7A1
All Species:
51.82
Human Site:
S133
Identified Species:
87.69
UniProt:
P49419
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49419
NP_001173.2
539
58487
S133
Q
V
L
G
S
L
V
S
L
E
M
G
K
I
L
Chimpanzee
Pan troglodytes
XP_001157473
539
58521
S133
Q
V
L
G
S
L
V
S
L
E
M
G
K
I
L
Rhesus Macaque
Macaca mulatta
XP_001096223
539
58507
S133
Q
V
L
G
S
L
V
S
L
E
M
G
K
I
L
Dog
Lupus familis
XP_538607
539
58565
S133
Q
I
L
G
N
L
V
S
L
E
M
G
K
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBF1
539
58843
S133
Q
L
L
G
R
L
V
S
L
E
M
G
K
I
L
Rat
Rattus norvegicus
Q64057
539
58730
S133
Q
L
L
G
R
L
V
S
L
E
M
G
K
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505897
617
66249
S211
Q
V
L
G
S
L
V
S
L
E
M
G
K
I
L
Chicken
Gallus gallus
O93344
518
56713
S125
A
V
L
A
T
M
E
S
L
N
S
G
K
P
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997889
511
55585
S105
K
A
L
G
S
L
M
S
L
E
M
G
K
V
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394614
527
56591
S119
K
P
L
G
Q
L
V
S
L
E
M
G
K
I
L
Nematode Worm
Caenorhab. elegans
P46562
531
56994
S123
Q
N
L
G
K
L
V
S
L
E
M
G
K
I
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002331178
508
54809
S103
Q
E
L
G
R
L
V
S
L
E
M
G
K
I
L
Maize
Zea mays
NP_001149126
509
54399
S104
H
H
L
G
R
L
V
S
L
E
M
G
K
I
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SYG7
508
54190
S103
D
Y
L
G
R
L
L
S
L
E
M
G
K
I
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.1
94.4
N.A.
88.3
88.8
N.A.
77.3
28.5
N.A.
80.1
N.A.
N.A.
56.2
62.7
N.A.
Protein Similarity:
100
99.6
98.5
97
N.A.
94.2
94
N.A.
83.6
47.3
N.A.
88.5
N.A.
N.A.
73.8
77.3
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
100
40
N.A.
66.6
N.A.
N.A.
80
80
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
53.3
N.A.
86.6
N.A.
N.A.
86.6
80
N.A.
Percent
Protein Identity:
56
56.2
N.A.
56.7
N.A.
N.A.
Protein Similarity:
70.8
69.7
N.A.
71.8
N.A.
N.A.
P-Site Identity:
86.6
80
N.A.
73.3
N.A.
N.A.
P-Site Similarity:
86.6
80
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
8
0
0
93
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
93
0
0
0
0
0
0
0
100
0
0
0
% G
% His:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
86
0
% I
% Lys:
15
0
0
0
8
0
0
0
0
0
0
0
100
0
0
% K
% Leu:
0
15
100
0
0
93
8
0
100
0
0
0
0
0
79
% L
% Met:
0
0
0
0
0
8
8
0
0
0
93
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
65
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
36
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
36
0
0
100
0
0
8
0
0
0
8
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
36
0
0
0
0
79
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _