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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC34 All Species: 32.73
Human Site: S106 Identified Species: 51.43
UniProt: P49427 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49427 NP_004350.1 236 26737 S106 P P V D D P Q S G E L P S E R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533965 205 22647 G76 P V D D P Q S G E L P S E R W
Cat Felis silvestris
Mouse Mus musculus Q8CFI2 235 26603 S106 P P V D D P Q S G E L P S E R
Rat Rattus norvegicus P62255 170 19491 L41 D L Y R W E V L I I G P P D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514141 236 26770 S106 P P V D D P Q S G E L P S E R
Chicken Gallus gallus XP_423237 235 26783 S106 P P V D D P Q S G E L P S E R
Frog Xenopus laevis NP_001079611 237 26829 S108 P P V D D P Q S G E L P S E R
Zebra Danio Brachydanio rerio NP_957252 241 27534 S109 P P V D D P Q S G E L P S E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25153 151 17134 T22 R L Q E D P P T G V S G A P T
Honey Bee Apis mellifera XP_394314 239 27348 S105 P P V D D P Q S G E L P C E R
Nematode Worm Caenorhab. elegans P34477 164 18920 K35 V D D N D I Y K W E V L V I G
Sea Urchin Strong. purpuratus XP_790380 244 27684 S109 P P V A D E Q S G E L P S E R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42540 166 18704 W37 D E K N I F E W S V T I I G P
Baker's Yeast Sacchar. cerevisiae P14682 295 34046 D108 Q S G D P M T D E P D A E T W
Red Bread Mold Neurospora crassa P52493 151 17245 A22 R M Q T D P P A G V S A S P V
Conservation
Percent
Protein Identity: 100 N.A. N.A. 77.1 N.A. 99.1 39.8 N.A. 91.5 96.1 89.8 82.9 N.A. 29.6 66.5 37.7 66.3
Protein Similarity: 100 N.A. N.A. 79.2 N.A. 99.5 51.2 N.A. 94 97.4 94.5 90 N.A. 42.7 81.1 50.4 78.2
P-Site Identity: 100 N.A. N.A. 13.3 N.A. 100 6.6 N.A. 100 100 100 100 N.A. 20 93.3 13.3 86.6
P-Site Similarity: 100 N.A. N.A. 13.3 N.A. 100 13.3 N.A. 100 100 100 100 N.A. 40 93.3 26.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. 38.5 31.1 27.5
Protein Similarity: N.A. N.A. N.A. 51.2 50.5 44
P-Site Identity: N.A. N.A. N.A. 0 6.6 26.6
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 0 7 0 0 0 14 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 14 7 14 60 74 0 0 7 0 0 7 0 0 7 0 % D
% Glu: 0 7 0 7 0 14 7 0 14 60 0 0 14 54 0 % E
% Phe: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 0 0 0 0 7 67 0 7 7 0 7 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 7 0 0 7 7 0 7 7 7 0 % I
% Lys: 0 0 7 0 0 0 0 7 0 0 0 0 0 0 0 % K
% Leu: 0 14 0 0 0 0 0 7 0 7 54 7 0 0 0 % L
% Met: 0 7 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 60 54 0 0 14 60 14 0 0 7 7 60 7 14 7 % P
% Gln: 7 0 14 0 0 7 54 0 0 0 0 0 0 0 0 % Q
% Arg: 14 0 0 7 0 0 0 0 0 0 0 0 0 7 54 % R
% Ser: 0 7 0 0 0 0 7 54 7 0 14 7 54 0 0 % S
% Thr: 0 0 0 7 0 0 7 7 0 0 7 0 0 7 14 % T
% Val: 7 7 54 0 0 0 7 0 0 20 7 0 7 0 7 % V
% Trp: 0 0 0 0 7 0 0 7 7 0 0 0 0 0 14 % W
% Tyr: 0 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _