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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC34
All Species:
32.73
Human Site:
S106
Identified Species:
51.43
UniProt:
P49427
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49427
NP_004350.1
236
26737
S106
P
P
V
D
D
P
Q
S
G
E
L
P
S
E
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533965
205
22647
G76
P
V
D
D
P
Q
S
G
E
L
P
S
E
R
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFI2
235
26603
S106
P
P
V
D
D
P
Q
S
G
E
L
P
S
E
R
Rat
Rattus norvegicus
P62255
170
19491
L41
D
L
Y
R
W
E
V
L
I
I
G
P
P
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514141
236
26770
S106
P
P
V
D
D
P
Q
S
G
E
L
P
S
E
R
Chicken
Gallus gallus
XP_423237
235
26783
S106
P
P
V
D
D
P
Q
S
G
E
L
P
S
E
R
Frog
Xenopus laevis
NP_001079611
237
26829
S108
P
P
V
D
D
P
Q
S
G
E
L
P
S
E
R
Zebra Danio
Brachydanio rerio
NP_957252
241
27534
S109
P
P
V
D
D
P
Q
S
G
E
L
P
S
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25153
151
17134
T22
R
L
Q
E
D
P
P
T
G
V
S
G
A
P
T
Honey Bee
Apis mellifera
XP_394314
239
27348
S105
P
P
V
D
D
P
Q
S
G
E
L
P
C
E
R
Nematode Worm
Caenorhab. elegans
P34477
164
18920
K35
V
D
D
N
D
I
Y
K
W
E
V
L
V
I
G
Sea Urchin
Strong. purpuratus
XP_790380
244
27684
S109
P
P
V
A
D
E
Q
S
G
E
L
P
S
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42540
166
18704
W37
D
E
K
N
I
F
E
W
S
V
T
I
I
G
P
Baker's Yeast
Sacchar. cerevisiae
P14682
295
34046
D108
Q
S
G
D
P
M
T
D
E
P
D
A
E
T
W
Red Bread Mold
Neurospora crassa
P52493
151
17245
A22
R
M
Q
T
D
P
P
A
G
V
S
A
S
P
V
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
77.1
N.A.
99.1
39.8
N.A.
91.5
96.1
89.8
82.9
N.A.
29.6
66.5
37.7
66.3
Protein Similarity:
100
N.A.
N.A.
79.2
N.A.
99.5
51.2
N.A.
94
97.4
94.5
90
N.A.
42.7
81.1
50.4
78.2
P-Site Identity:
100
N.A.
N.A.
13.3
N.A.
100
6.6
N.A.
100
100
100
100
N.A.
20
93.3
13.3
86.6
P-Site Similarity:
100
N.A.
N.A.
13.3
N.A.
100
13.3
N.A.
100
100
100
100
N.A.
40
93.3
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.5
31.1
27.5
Protein Similarity:
N.A.
N.A.
N.A.
51.2
50.5
44
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
7
0
0
0
14
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
14
7
14
60
74
0
0
7
0
0
7
0
0
7
0
% D
% Glu:
0
7
0
7
0
14
7
0
14
60
0
0
14
54
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
7
67
0
7
7
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
7
0
0
7
7
0
7
7
7
0
% I
% Lys:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% K
% Leu:
0
14
0
0
0
0
0
7
0
7
54
7
0
0
0
% L
% Met:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
60
54
0
0
14
60
14
0
0
7
7
60
7
14
7
% P
% Gln:
7
0
14
0
0
7
54
0
0
0
0
0
0
0
0
% Q
% Arg:
14
0
0
7
0
0
0
0
0
0
0
0
0
7
54
% R
% Ser:
0
7
0
0
0
0
7
54
7
0
14
7
54
0
0
% S
% Thr:
0
0
0
7
0
0
7
7
0
0
7
0
0
7
14
% T
% Val:
7
7
54
0
0
0
7
0
0
20
7
0
7
0
7
% V
% Trp:
0
0
0
0
7
0
0
7
7
0
0
0
0
0
14
% W
% Tyr:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _