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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC34 All Species: 28.48
Human Site: S111 Identified Species: 44.76
UniProt: P49427 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49427 NP_004350.1 236 26737 S111 P Q S G E L P S E R W N P T Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533965 205 22647 E81 Q S G E L P S E R W N P T Q N
Cat Felis silvestris
Mouse Mus musculus Q8CFI2 235 26603 S111 P Q S G E L P S E R W N P T Q
Rat Rattus norvegicus P62255 170 19491 P46 E V L I I G P P D T L Y E G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514141 236 26770 S111 P Q S G E L P S E R W N P T Q
Chicken Gallus gallus XP_423237 235 26783 S111 P Q S G E L P S E R W N P T Q
Frog Xenopus laevis NP_001079611 237 26829 S113 P Q S G E L P S E R W N P T Q
Zebra Danio Brachydanio rerio NP_957252 241 27534 S114 P Q S G E L P S E R W N P T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25153 151 17134 A27 P P T G V S G A P T D N N I M
Honey Bee Apis mellifera XP_394314 239 27348 C110 P Q S G E L P C E R W N P T Q
Nematode Worm Caenorhab. elegans P34477 164 18920 V40 I Y K W E V L V I G P P D T L
Sea Urchin Strong. purpuratus XP_790380 244 27684 S114 E Q S G E L P S E R W N P T Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42540 166 18704 I42 F E W S V T I I G P P D T L Y
Baker's Yeast Sacchar. cerevisiae P14682 295 34046 E113 M T D E P D A E T W S P V Q T
Red Bread Mold Neurospora crassa P52493 151 17245 S27 P P A G V S A S P V P D N V M
Conservation
Percent
Protein Identity: 100 N.A. N.A. 77.1 N.A. 99.1 39.8 N.A. 91.5 96.1 89.8 82.9 N.A. 29.6 66.5 37.7 66.3
Protein Similarity: 100 N.A. N.A. 79.2 N.A. 99.5 51.2 N.A. 94 97.4 94.5 90 N.A. 42.7 81.1 50.4 78.2
P-Site Identity: 100 N.A. N.A. 0 N.A. 100 6.6 N.A. 100 100 100 100 N.A. 20 93.3 13.3 93.3
P-Site Similarity: 100 N.A. N.A. 0 N.A. 100 13.3 N.A. 100 100 100 100 N.A. 33.3 93.3 20 93.3
Percent
Protein Identity: N.A. N.A. N.A. 38.5 31.1 27.5
Protein Similarity: N.A. N.A. N.A. 51.2 50.5 44
P-Site Identity: N.A. N.A. N.A. 0 0 20
P-Site Similarity: N.A. N.A. N.A. 13.3 0 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 14 7 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 7 0 0 7 0 7 14 7 0 0 % D
% Glu: 14 7 0 14 60 0 0 14 54 0 0 0 7 0 0 % E
% Phe: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 67 0 7 7 0 7 7 0 0 0 7 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 7 7 0 7 7 7 0 0 0 0 7 0 % I
% Lys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 7 0 7 54 7 0 0 0 7 0 0 7 7 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 14 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 7 60 14 0 7 % N
% Pro: 60 14 0 0 7 7 60 7 14 7 20 20 54 0 0 % P
% Gln: 7 54 0 0 0 0 0 0 0 0 0 0 0 14 54 % Q
% Arg: 0 0 0 0 0 0 0 0 7 54 0 0 0 0 0 % R
% Ser: 0 7 54 7 0 14 7 54 0 0 7 0 0 0 0 % S
% Thr: 0 7 7 0 0 7 0 0 7 14 0 0 14 60 7 % T
% Val: 0 7 0 0 20 7 0 7 0 7 0 0 7 7 0 % V
% Trp: 0 0 7 7 0 0 0 0 0 14 54 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 0 0 0 0 7 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _