Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC34 All Species: 24.85
Human Site: S203 Identified Species: 39.05
UniProt: P49427 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49427 NP_004350.1 236 26737 S203 A P A P D E G S D L F Y D D Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533965 205 22647 D173 P A P D E G S D L F Y D D Y Y
Cat Felis silvestris
Mouse Mus musculus Q8CFI2 235 26603 S203 A P A P D E G S D L F Y D D Y
Rat Rattus norvegicus P62255 170 19491 N138 P N G D S P A N V D A A K E W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514141 236 26770 S203 V P G S D E G S D L F Y D D Y
Chicken Gallus gallus XP_423237 235 26783 S203 T P A P D E G S D L F Y D D Y
Frog Xenopus laevis NP_001079611 237 26829 S205 A P A P D E G S D L F Y D D Y
Zebra Danio Brachydanio rerio NP_957252 241 27534 S206 A P P A D E G S N F F Y D D Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25153 151 17134 N119 L L S D P N P N S P A N S T A
Honey Bee Apis mellifera XP_394314 239 27348 L202 A R P A E Q Q L D M T D F Y D
Nematode Worm Caenorhab. elegans P34477 164 18920 E132 M L T D P N F E S P A N V D A
Sea Urchin Strong. purpuratus XP_790380 244 27684 S206 E T P Q S Q S S V D L A D F Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42540 166 18704 S134 L S G P N D E S P A N V E A A
Baker's Yeast Sacchar. cerevisiae P14682 295 34046 Y205 D M A D N F W Y D S D L D D D
Red Bread Mold Neurospora crassa P52493 151 17245 G119 L L N D P N T G S R A N V E A
Conservation
Percent
Protein Identity: 100 N.A. N.A. 77.1 N.A. 99.1 39.8 N.A. 91.5 96.1 89.8 82.9 N.A. 29.6 66.5 37.7 66.3
Protein Similarity: 100 N.A. N.A. 79.2 N.A. 99.5 51.2 N.A. 94 97.4 94.5 90 N.A. 42.7 81.1 50.4 78.2
P-Site Identity: 100 N.A. N.A. 13.3 N.A. 100 0 N.A. 80 93.3 100 73.3 N.A. 0 13.3 6.6 20
P-Site Similarity: 100 N.A. N.A. 26.6 N.A. 100 20 N.A. 80 93.3 100 80 N.A. 13.3 33.3 6.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 38.5 31.1 27.5
Protein Similarity: N.A. N.A. N.A. 51.2 50.5 44
P-Site Identity: N.A. N.A. N.A. 13.3 26.6 0
P-Site Similarity: N.A. N.A. N.A. 33.3 33.3 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 7 34 14 0 0 7 0 0 7 27 14 0 7 27 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 40 40 7 0 7 47 14 7 14 60 54 14 % D
% Glu: 7 0 0 0 14 40 7 7 0 0 0 0 7 14 0 % E
% Phe: 0 0 0 0 0 7 7 0 0 14 40 0 7 7 0 % F
% Gly: 0 0 20 0 0 7 40 7 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % K
% Leu: 20 20 0 0 0 0 0 7 7 34 7 7 0 0 0 % L
% Met: 7 7 0 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 0 7 7 0 14 20 0 14 7 0 7 20 0 0 0 % N
% Pro: 14 40 27 34 20 7 7 0 7 14 0 0 0 0 0 % P
% Gln: 0 0 0 7 0 14 7 0 0 0 0 0 0 0 0 % Q
% Arg: 0 7 0 0 0 0 0 0 0 7 0 0 0 0 0 % R
% Ser: 0 7 7 7 14 0 14 54 20 7 0 0 7 0 0 % S
% Thr: 7 7 7 0 0 0 7 0 0 0 7 0 0 7 0 % T
% Val: 7 0 0 0 0 0 0 0 14 0 0 7 14 0 0 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 7 40 0 14 54 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _