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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC34
All Species:
13.64
Human Site:
S222
Identified Species:
21.43
UniProt:
P49427
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49427
NP_004350.1
236
26737
S222
E
V
E
E
E
A
D
S
C
F
G
D
D
E
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533965
205
22647
C192
A
E
A
E
A
D
S
C
F
G
D
D
E
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFI2
235
26603
C222
E
V
E
E
A
D
S
C
F
G
D
E
E
D
D
Rat
Rattus norvegicus
P62255
170
19491
V157
N
G
E
F
K
R
K
V
A
R
C
V
R
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514141
236
26770
S222
A
V
E
E
E
A
G
S
C
F
G
E
D
G
D
Chicken
Gallus gallus
XP_423237
235
26783
S222
E
M
E
E
E
A
D
S
C
Y
G
D
E
D
D
Frog
Xenopus laevis
NP_001079611
237
26829
S224
E
M
E
E
D
E
D
S
C
Y
E
G
Q
D
D
Zebra Danio
Brachydanio rerio
NP_957252
241
27534
E225
D
L
D
D
D
E
E
E
G
E
D
C
C
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25153
151
17134
E138
K
E
N
R
R
E
Y
E
K
R
V
K
A
C
V
Honey Bee
Apis mellifera
XP_394314
239
27348
E221
L
D
D
D
D
D
D
E
Q
M
S
A
S
D
Y
Nematode Worm
Caenorhab. elegans
P34477
164
18920
K151
R
E
N
Y
A
E
F
K
K
K
V
A
Q
C
V
Sea Urchin
Strong. purpuratus
XP_790380
244
27684
D225
Y
G
V
E
D
D
D
D
D
D
D
D
E
C
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42540
166
18704
K153
D
K
R
D
E
F
K
K
K
V
S
R
C
V
R
Baker's Yeast
Sacchar. cerevisiae
P14682
295
34046
Y224
V
I
L
Q
D
D
D
Y
D
D
G
N
N
H
I
Red Bread Mold
Neurospora crassa
P52493
151
17245
H138
K
D
N
R
K
E
Y
H
K
R
V
R
E
T
V
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
77.1
N.A.
99.1
39.8
N.A.
91.5
96.1
89.8
82.9
N.A.
29.6
66.5
37.7
66.3
Protein Similarity:
100
N.A.
N.A.
79.2
N.A.
99.5
51.2
N.A.
94
97.4
94.5
90
N.A.
42.7
81.1
50.4
78.2
P-Site Identity:
100
N.A.
N.A.
20
N.A.
33.3
6.6
N.A.
73.3
73.3
46.6
6.6
N.A.
0
6.6
0
20
P-Site Similarity:
100
N.A.
N.A.
33.3
N.A.
53.3
20
N.A.
80
100
73.3
46.6
N.A.
6.6
33.3
0
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.5
31.1
27.5
Protein Similarity:
N.A.
N.A.
N.A.
51.2
50.5
44
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
46.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
7
0
20
20
0
0
7
0
0
14
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
14
27
0
7
7
14
20
0
% C
% Asp:
14
14
14
20
34
34
40
7
14
14
27
27
14
34
47
% D
% Glu:
27
20
40
47
27
34
7
20
0
7
7
14
34
7
0
% E
% Phe:
0
0
0
7
0
7
7
0
14
14
0
0
0
0
0
% F
% Gly:
0
14
0
0
0
0
7
0
7
14
27
7
0
7
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
14
7
0
0
14
0
14
14
27
7
0
7
0
7
0
% K
% Leu:
7
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
14
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
7
0
20
0
0
0
0
0
0
0
0
7
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
0
7
0
0
0
14
0
0
% Q
% Arg:
7
0
7
14
7
7
0
0
0
20
0
14
7
0
7
% R
% Ser:
0
0
0
0
0
0
14
27
0
0
14
0
7
0
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% T
% Val:
7
20
7
0
0
0
0
7
0
7
20
7
0
7
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
0
14
7
0
14
0
0
0
7
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _