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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC34
All Species:
5.73
Human Site:
S236
Identified Species:
9
UniProt:
P49427
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49427
NP_004350.1
236
26737
S236
D
D
S
G
T
E
E
S
_
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533965
205
22647
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFI2
235
26603
Rat
Rattus norvegicus
P62255
170
19491
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514141
236
26770
S236
D
D
S
G
N
E
E
S
_
_
_
_
_
_
_
Chicken
Gallus gallus
XP_423237
235
26783
Frog
Xenopus laevis
NP_001079611
237
26829
Zebra Danio
Brachydanio rerio
NP_957252
241
27534
E239
D
E
D
D
S
G
T
E
D
S
_
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25153
151
17134
Honey Bee
Apis mellifera
XP_394314
239
27348
G235
Y
E
D
G
D
D
S
G
N
G
E
S
_
_
_
Nematode Worm
Caenorhab. elegans
P34477
164
18920
Sea Urchin
Strong. purpuratus
XP_790380
244
27684
S239
Y
Y
D
D
E
D
D
S
G
N
G
E
S
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42540
166
18704
Baker's Yeast
Sacchar. cerevisiae
P14682
295
34046
V238
I
P
F
E
D
D
D
V
Y
N
Y
N
D
N
D
Red Bread Mold
Neurospora crassa
P52493
151
17245
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
77.1
N.A.
99.1
39.8
N.A.
91.5
96.1
89.8
82.9
N.A.
29.6
66.5
37.7
66.3
Protein Similarity:
100
N.A.
N.A.
79.2
N.A.
99.5
51.2
N.A.
94
97.4
94.5
90
N.A.
42.7
81.1
50.4
78.2
P-Site Identity:
100
N.A.
N.A.
0
N.A.
0
0
N.A.
87.5
0
0
10
N.A.
0
8.3
0
7.6
P-Site Similarity:
100
N.A.
N.A.
0
N.A.
0
0
N.A.
87.5
0
0
30
N.A.
0
33.3
0
38.4
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.5
31.1
27.5
Protein Similarity:
N.A.
N.A.
N.A.
51.2
50.5
44
P-Site Identity:
N.A.
N.A.
N.A.
0
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
0
26.6
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
14
20
14
14
20
14
0
7
0
0
0
7
0
7
% D
% Glu:
0
14
0
7
7
14
14
7
0
0
7
7
0
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
20
0
7
0
7
7
7
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
7
14
0
7
0
7
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
14
0
7
0
7
20
0
7
0
7
7
0
0
% S
% Thr:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
14
7
0
0
0
0
0
0
7
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
14
14
20
20
27
34
34
% _