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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC34 All Species: 13.64
Human Site: T162 Identified Species: 21.43
UniProt: P49427 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49427 NP_004350.1 236 26737 T162 K G K D R E Y T D I I R K Q V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533965 205 22647 D132 G K D R E Y T D I I R K Q V L
Cat Felis silvestris
Mouse Mus musculus Q8CFI2 235 26603 T162 K G K D R E Y T D I I R K Q V
Rat Rattus norvegicus P62255 170 19491 P97 C I S I L H E P G E D K Y G Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514141 236 26770 V162 K G K D R E Y V D I I R K Q V
Chicken Gallus gallus XP_423237 235 26783 T162 K G K D R E Y T D I I R K Q V
Frog Xenopus laevis NP_001079611 237 26829 T164 K G R D K E Y T D I I R K Q V
Zebra Danio Brachydanio rerio NP_957252 241 27534 A165 K G K D R E Y A E I I R K Q V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25153 151 17134 H78 R F V S K V F H P N V Y A D G
Honey Bee Apis mellifera XP_394314 239 27348 E161 K G K D K E Y E N I I R K Q A
Nematode Worm Caenorhab. elegans P34477 164 18920 I91 E G N V C I S I L H D P G D D
Sea Urchin Strong. purpuratus XP_790380 244 27684 E165 K G K N K E Y E D L I K K Q V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42540 166 18704 L93 G R V C I S I L H P P G D D P
Baker's Yeast Sacchar. cerevisiae P14682 295 34046 V164 K Q R V K M E V E R S K Q D I
Red Bread Mold Neurospora crassa P52493 151 17245 H78 K F I S E M F H P N V Y A T G
Conservation
Percent
Protein Identity: 100 N.A. N.A. 77.1 N.A. 99.1 39.8 N.A. 91.5 96.1 89.8 82.9 N.A. 29.6 66.5 37.7 66.3
Protein Similarity: 100 N.A. N.A. 79.2 N.A. 99.5 51.2 N.A. 94 97.4 94.5 90 N.A. 42.7 81.1 50.4 78.2
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 100 0 N.A. 93.3 100 86.6 86.6 N.A. 0 73.3 6.6 66.6
P-Site Similarity: 100 N.A. N.A. 26.6 N.A. 100 6.6 N.A. 93.3 100 100 93.3 N.A. 26.6 86.6 13.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 38.5 31.1 27.5
Protein Similarity: N.A. N.A. N.A. 51.2 50.5 44
P-Site Identity: N.A. N.A. N.A. 0 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 0 46.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 7 0 0 0 0 14 0 7 % A
% Cys: 7 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 47 0 0 0 7 40 0 14 0 7 27 7 % D
% Glu: 7 0 0 0 14 54 14 14 14 7 0 0 0 0 0 % E
% Phe: 0 14 0 0 0 0 14 0 0 0 0 0 0 0 0 % F
% Gly: 14 60 0 0 0 0 0 0 7 0 0 7 7 7 14 % G
% His: 0 0 0 0 0 7 0 14 7 7 0 0 0 0 0 % H
% Ile: 0 7 7 7 7 7 7 7 7 54 54 0 0 0 7 % I
% Lys: 67 7 47 0 34 0 0 0 0 0 0 27 54 0 0 % K
% Leu: 0 0 0 0 7 0 0 7 7 7 0 0 0 0 7 % L
% Met: 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 7 0 0 0 0 7 14 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 7 14 7 7 7 0 0 7 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 0 0 14 54 0 % Q
% Arg: 7 7 14 7 34 0 0 0 0 7 7 47 0 0 0 % R
% Ser: 0 0 7 14 0 7 7 0 0 0 7 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 7 27 0 0 0 0 0 7 0 % T
% Val: 0 0 14 14 0 7 0 14 0 0 14 0 0 7 47 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 54 0 0 0 0 14 7 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _