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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC34
All Species:
32.12
Human Site:
Y161
Identified Species:
50.48
UniProt:
P49427
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49427
NP_004350.1
236
26737
Y161
S
K
G
K
D
R
E
Y
T
D
I
I
R
K
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533965
205
22647
T131
K
G
K
D
R
E
Y
T
D
I
I
R
K
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFI2
235
26603
Y161
S
K
G
K
D
R
E
Y
T
D
I
I
R
K
Q
Rat
Rattus norvegicus
P62255
170
19491
E96
V
C
I
S
I
L
H
E
P
G
E
D
K
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514141
236
26770
Y161
S
K
G
K
D
R
E
Y
V
D
I
I
R
K
Q
Chicken
Gallus gallus
XP_423237
235
26783
Y161
S
K
G
K
D
R
E
Y
T
D
I
I
R
K
Q
Frog
Xenopus laevis
NP_001079611
237
26829
Y163
S
K
G
R
D
K
E
Y
T
D
I
I
R
K
Q
Zebra Danio
Brachydanio rerio
NP_957252
241
27534
Y164
S
K
G
K
D
R
E
Y
A
E
I
I
R
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25153
151
17134
F77
V
R
F
V
S
K
V
F
H
P
N
V
Y
A
D
Honey Bee
Apis mellifera
XP_394314
239
27348
Y160
S
K
G
K
D
K
E
Y
E
N
I
I
R
K
Q
Nematode Worm
Caenorhab. elegans
P34477
164
18920
S90
K
E
G
N
V
C
I
S
I
L
H
D
P
G
D
Sea Urchin
Strong. purpuratus
XP_790380
244
27684
Y164
S
K
G
K
N
K
E
Y
E
D
L
I
K
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42540
166
18704
I92
D
G
R
V
C
I
S
I
L
H
P
P
G
D
D
Baker's Yeast
Sacchar. cerevisiae
P14682
295
34046
E163
Y
K
Q
R
V
K
M
E
V
E
R
S
K
Q
D
Red Bread Mold
Neurospora crassa
P52493
151
17245
F77
V
K
F
I
S
E
M
F
H
P
N
V
Y
A
T
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
77.1
N.A.
99.1
39.8
N.A.
91.5
96.1
89.8
82.9
N.A.
29.6
66.5
37.7
66.3
Protein Similarity:
100
N.A.
N.A.
79.2
N.A.
99.5
51.2
N.A.
94
97.4
94.5
90
N.A.
42.7
81.1
50.4
78.2
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
100
0
N.A.
93.3
100
86.6
86.6
N.A.
0
80
6.6
66.6
P-Site Similarity:
100
N.A.
N.A.
20
N.A.
100
6.6
N.A.
93.3
100
100
93.3
N.A.
26.6
93.3
13.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.5
31.1
27.5
Protein Similarity:
N.A.
N.A.
N.A.
51.2
50.5
44
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
0
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
0
0
0
0
14
0
% A
% Cys:
0
7
0
0
7
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
47
0
0
0
7
40
0
14
0
7
27
% D
% Glu:
0
7
0
0
0
14
54
14
14
14
7
0
0
0
0
% E
% Phe:
0
0
14
0
0
0
0
14
0
0
0
0
0
0
0
% F
% Gly:
0
14
60
0
0
0
0
0
0
7
0
0
7
7
7
% G
% His:
0
0
0
0
0
0
7
0
14
7
7
0
0
0
0
% H
% Ile:
0
0
7
7
7
7
7
7
7
7
54
54
0
0
0
% I
% Lys:
14
67
7
47
0
34
0
0
0
0
0
0
27
54
0
% K
% Leu:
0
0
0
0
0
7
0
0
7
7
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
7
0
0
0
0
7
14
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
14
7
7
7
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
0
0
14
54
% Q
% Arg:
0
7
7
14
7
34
0
0
0
0
7
7
47
0
0
% R
% Ser:
54
0
0
7
14
0
7
7
0
0
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
7
27
0
0
0
0
0
7
% T
% Val:
20
0
0
14
14
0
7
0
14
0
0
14
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
7
54
0
0
0
0
14
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _