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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC34 All Species: 21.52
Human Site: Y211 Identified Species: 33.81
UniProt: P49427 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49427 NP_004350.1 236 26737 Y211 D L F Y D D Y Y E D G E V E E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533965 205 22647 E181 L F Y D D Y Y E D G E A E A E
Cat Felis silvestris
Mouse Mus musculus Q8CFI2 235 26603 Y211 D L F Y D D Y Y E D G E V E E
Rat Rattus norvegicus P62255 170 19491 R146 V D A A K E W R E D R N G E F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514141 236 26770 Y211 D L F Y D D Y Y E D D A V E E
Chicken Gallus gallus XP_423237 235 26783 Y211 D L F Y D D Y Y E D D E M E E
Frog Xenopus laevis NP_001079611 237 26829 Y213 D L F Y D D Y Y E D D E M E E
Zebra Danio Brachydanio rerio NP_957252 241 27534 Y214 N F F Y D D Y Y D D E D L D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25153 151 17134 A127 S P A N S T A A Q L Y K E N R
Honey Bee Apis mellifera XP_394314 239 27348 D210 D M T D F Y D D E Y E L D D D
Nematode Worm Caenorhab. elegans P34477 164 18920 A140 S P A N V D A A K M Q R E N Y
Sea Urchin Strong. purpuratus XP_790380 244 27684 D214 V D L A D F Y D D G D Y G V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42540 166 18704 K142 P A N V E A A K E W R D K R D
Baker's Yeast Sacchar. cerevisiae P14682 295 34046 E213 D S D L D D D E N G S V I L Q
Red Bread Mold Neurospora crassa P52493 151 17245 S127 S R A N V E A S N L Y K D N R
Conservation
Percent
Protein Identity: 100 N.A. N.A. 77.1 N.A. 99.1 39.8 N.A. 91.5 96.1 89.8 82.9 N.A. 29.6 66.5 37.7 66.3
Protein Similarity: 100 N.A. N.A. 79.2 N.A. 99.5 51.2 N.A. 94 97.4 94.5 90 N.A. 42.7 81.1 50.4 78.2
P-Site Identity: 100 N.A. N.A. 20 N.A. 100 20 N.A. 86.6 86.6 86.6 46.6 N.A. 0 13.3 6.6 20
P-Site Similarity: 100 N.A. N.A. 33.3 N.A. 100 33.3 N.A. 86.6 93.3 93.3 86.6 N.A. 13.3 33.3 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 38.5 31.1 27.5
Protein Similarity: N.A. N.A. N.A. 51.2 50.5 44
P-Site Identity: N.A. N.A. N.A. 6.6 20 0
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 27 14 0 7 27 14 0 0 0 14 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 47 14 7 14 60 54 14 14 20 47 27 14 14 14 20 % D
% Glu: 0 0 0 0 7 14 0 14 54 0 20 27 20 40 47 % E
% Phe: 0 14 40 0 7 7 0 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 0 0 0 0 0 0 0 20 14 0 14 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % I
% Lys: 0 0 0 0 7 0 0 7 7 0 0 14 7 0 0 % K
% Leu: 7 34 7 7 0 0 0 0 0 14 0 7 7 7 0 % L
% Met: 0 7 0 0 0 0 0 0 0 7 0 0 14 0 0 % M
% Asn: 7 0 7 20 0 0 0 0 14 0 0 7 0 20 0 % N
% Pro: 7 14 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 7 0 7 0 0 0 7 % Q
% Arg: 0 7 0 0 0 0 0 7 0 0 14 7 0 7 14 % R
% Ser: 20 7 0 0 7 0 0 7 0 0 7 0 0 0 0 % S
% Thr: 0 0 7 0 0 7 0 0 0 0 0 0 0 0 0 % T
% Val: 14 0 0 7 14 0 0 0 0 0 0 7 20 7 0 % V
% Trp: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 7 40 0 14 54 40 0 7 14 7 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _