Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC34 All Species: 29.39
Human Site: Y53 Identified Species: 46.19
UniProt: P49427 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49427 NP_004350.1 236 26737 Y53 F G P P N T Y Y E G G Y F K A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533965 205 22647 G23 P S A N C V R G A C A D E A R
Cat Felis silvestris
Mouse Mus musculus Q8CFI2 235 26603 Y53 F G P P N T Y Y E G G Y F K A
Rat Rattus norvegicus P62255 170 19491
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514141 236 26770 Y53 F G P P N T Y Y E G G Y F K A
Chicken Gallus gallus XP_423237 235 26783 Y53 F G P P N T Y Y E G G Y F K A
Frog Xenopus laevis NP_001079611 237 26829 Y55 F G P P N T L Y E G G Y F K A
Zebra Danio Brachydanio rerio NP_957252 241 27534 Y56 F G P P N T H Y E G G Y F K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25153 151 17134
Honey Bee Apis mellifera XP_394314 239 27348 Y52 F G P P D T L Y Q G G Y F K A
Nematode Worm Caenorhab. elegans P34477 164 18920
Sea Urchin Strong. purpuratus XP_790380 244 27684 E56 G P P G T L Y E G G Y F K A M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42540 166 18704
Baker's Yeast Sacchar. cerevisiae P14682 295 34046 Y55 V L N E D S I Y H G G F F K A
Red Bread Mold Neurospora crassa P52493 151 17245
Conservation
Percent
Protein Identity: 100 N.A. N.A. 77.1 N.A. 99.1 39.8 N.A. 91.5 96.1 89.8 82.9 N.A. 29.6 66.5 37.7 66.3
Protein Similarity: 100 N.A. N.A. 79.2 N.A. 99.5 51.2 N.A. 94 97.4 94.5 90 N.A. 42.7 81.1 50.4 78.2
P-Site Identity: 100 N.A. N.A. 0 N.A. 100 0 N.A. 100 100 93.3 93.3 N.A. 0 80 0 20
P-Site Similarity: 100 N.A. N.A. 0 N.A. 100 0 N.A. 100 100 93.3 100 N.A. 0 93.3 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. 38.5 31.1 27.5
Protein Similarity: N.A. N.A. N.A. 51.2 50.5 44
P-Site Identity: N.A. N.A. N.A. 0 40 0
P-Site Similarity: N.A. N.A. N.A. 0 60 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 0 0 7 0 7 0 0 14 54 % A
% Cys: 0 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 0 0 0 14 0 0 0 0 0 0 7 0 0 0 % D
% Glu: 0 0 0 7 0 0 0 7 40 0 0 0 7 0 0 % E
% Phe: 47 0 0 0 0 0 0 0 0 0 0 14 54 0 0 % F
% Gly: 7 47 0 7 0 0 0 7 7 60 54 0 0 0 0 % G
% His: 0 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 7 54 0 % K
% Leu: 0 7 0 0 0 7 14 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 0 7 7 40 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 7 54 47 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % R
% Ser: 0 7 0 0 0 7 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 7 47 0 0 0 0 0 0 0 0 0 % T
% Val: 7 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 34 54 0 0 7 47 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _