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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP1
All Species:
9.39
Human Site:
S252
Identified Species:
22.96
UniProt:
P49441
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49441
NP_001122400.1
399
43998
S252
T
H
T
G
N
T
G
S
E
A
A
F
S
P
S
Chimpanzee
Pan troglodytes
XP_516227
399
43949
S252
T
H
T
G
N
T
G
S
E
A
A
F
S
P
S
Rhesus Macaque
Macaca mulatta
XP_001095311
399
43851
S252
I
H
A
G
N
T
G
S
E
A
A
F
S
P
S
Dog
Lupus familis
XP_536004
452
48733
G304
P
R
A
A
G
G
A
G
P
E
A
G
Q
P
R
Cat
Felis silvestris
Mouse
Mus musculus
P49442
396
43328
E252
Q
T
E
N
S
D
R
E
F
S
S
P
F
S
A
Rat
Rattus norvegicus
Q9Z1N4
308
33156
Q181
G
L
G
A
F
G
F
Q
L
K
E
A
P
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083274
338
37089
L210
S
A
E
T
K
D
I
L
S
S
L
S
T
V
C
Zebra Danio
Brachydanio rerio
Q2YDR3
341
37413
R212
E
G
S
N
V
A
P
R
D
S
Y
N
T
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731872
375
40694
D242
T
V
R
A
H
N
C
D
F
E
A
R
D
E
N
Honey Bee
Apis mellifera
XP_393343
363
40298
S236
E
N
D
I
G
K
C
S
I
V
K
E
H
N
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.4
68.1
N.A.
80.9
26
N.A.
N.A.
N.A.
47.6
21
N.A.
38.3
43.1
N.A.
N.A.
Protein Similarity:
100
99.7
98.2
74.3
N.A.
89.2
43.3
N.A.
N.A.
N.A.
61.4
37
N.A.
56.6
59.1
N.A.
N.A.
P-Site Identity:
100
100
86.6
13.3
N.A.
0
0
N.A.
N.A.
N.A.
0
6.6
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
86.6
13.3
N.A.
26.6
0
N.A.
N.A.
N.A.
20
33.3
N.A.
26.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
20
30
0
10
10
0
0
30
50
10
0
10
10
% A
% Cys:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
10
0
0
20
0
10
10
0
0
0
10
0
0
% D
% Glu:
20
0
20
0
0
0
0
10
30
20
10
10
0
10
0
% E
% Phe:
0
0
0
0
10
0
10
0
20
0
0
30
10
0
0
% F
% Gly:
10
10
10
30
20
20
30
10
0
0
0
10
0
0
10
% G
% His:
0
30
0
0
10
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
10
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
10
0
0
0
10
10
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
10
10
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
20
30
10
0
0
0
0
0
10
0
20
20
% N
% Pro:
10
0
0
0
0
0
10
0
10
0
0
10
10
40
0
% P
% Gln:
10
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% Q
% Arg:
0
10
10
0
0
0
10
10
0
0
0
10
0
0
10
% R
% Ser:
10
0
10
0
10
0
0
40
10
30
10
10
30
10
40
% S
% Thr:
30
10
20
10
0
30
0
0
0
0
0
0
20
0
0
% T
% Val:
0
10
0
0
10
0
0
0
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _