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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLUD2
All Species:
19.09
Human Site:
S391
Identified Species:
35
UniProt:
P49448
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49448
NP_036216.2
558
61434
S391
T
E
K
Q
L
T
K
S
N
A
P
R
V
K
A
Chimpanzee
Pan troglodytes
Q64HZ8
558
61420
S391
T
E
K
Q
L
T
K
S
N
A
P
R
V
K
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540979
479
53188
P320
S
D
G
G
I
W
N
P
D
G
I
D
P
K
E
Cat
Felis silvestris
Mouse
Mus musculus
P26443
558
61318
S391
S
E
K
Q
L
T
K
S
N
A
P
R
V
K
A
Rat
Rattus norvegicus
P10860
558
61397
S391
S
E
K
Q
L
T
K
S
N
A
P
R
V
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P00368
503
55179
A344
A
N
A
H
K
V
K
A
K
I
I
A
E
G
A
Frog
Xenopus laevis
NP_001087023
540
59547
S373
S
E
K
Q
L
T
K
S
N
A
H
K
I
K
A
Zebra Danio
Brachydanio rerio
NP_997741
544
60096
K377
S
E
K
Q
L
T
K
K
N
A
N
N
I
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54385
562
62518
S382
A
V
E
K
V
I
T
S
E
N
A
N
R
I
Q
Honey Bee
Apis mellifera
XP_392776
553
61624
K386
A
I
E
K
V
I
N
K
D
N
A
S
F
I
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789257
558
61370
D377
G
E
K
Q
I
T
A
D
N
A
H
D
I
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43260
411
44004
Q252
V
D
G
L
D
I
A
Q
L
V
K
H
S
A
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38946
411
44681
A252
P
E
G
I
D
I
N
A
L
I
K
H
K
D
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
N.A.
75.2
N.A.
93.9
93
N.A.
N.A.
80.1
84
81.5
N.A.
66.3
67.5
N.A.
71.3
Protein Similarity:
100
99.6
N.A.
79.2
N.A.
96.4
95.6
N.A.
N.A.
84.9
91.5
90.5
N.A.
79.1
80.8
N.A.
82.9
P-Site Identity:
100
100
N.A.
6.6
N.A.
93.3
93.3
N.A.
N.A.
13.3
73.3
66.6
N.A.
6.6
0
N.A.
53.3
P-Site Similarity:
100
100
N.A.
33.3
N.A.
100
100
N.A.
N.A.
20
93.3
80
N.A.
26.6
26.6
N.A.
66.6
Percent
Protein Identity:
N.A.
33.3
N.A.
34.5
N.A.
N.A.
Protein Similarity:
N.A.
47.4
N.A.
47.8
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
8
0
0
0
16
16
0
54
16
8
0
8
70
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
16
0
0
8
16
0
0
16
0
8
0
% D
% Glu:
0
62
16
0
0
0
0
0
8
0
0
0
8
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
24
8
0
0
0
0
0
8
0
0
0
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
16
16
0
0
0
% H
% Ile:
0
8
0
8
16
31
0
0
0
16
16
0
24
16
0
% I
% Lys:
0
0
54
16
8
0
54
16
8
0
16
8
8
62
0
% K
% Leu:
0
0
0
8
47
0
0
0
16
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
24
0
54
16
8
16
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
8
0
0
31
0
8
0
0
% P
% Gln:
0
0
0
54
0
0
0
8
0
0
0
0
0
0
16
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
31
8
0
0
% R
% Ser:
39
0
0
0
0
0
0
47
0
0
0
8
8
0
0
% S
% Thr:
16
0
0
0
0
54
8
0
0
0
0
0
0
0
0
% T
% Val:
8
8
0
0
16
8
0
0
0
8
0
0
31
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _